Euphohyrisnoids A and B, Two Highly Rearranged Lathyrane Diterpenoids from .

Org Lett

School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong 510006, People's Republic of China.

Published: December 2021

Euphohyrisnoids A () and B (), two highly rearranged lathyrane diterpenoids featuring a unique tetracyclo[10.2.2.0.0]cetane and tricyclo[8.4.1.0]pentadecane skeleton, respectively, were isolated from the seeds of . Their structures were determined by detailed spectroscopic analysis and were further confirmed by single-crystal X-ray diffraction. significantly inhibited adipogenesis in 3T3-L1 adipocytes by retarding cell differentiation at the early stage.

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Source
http://dx.doi.org/10.1021/acs.orglett.1c03812DOI Listing

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