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Mechanical and Energy Evolution Characteristics of Fractured Sandstone Materials: A True Triaxial Experimental Study.
Materials (Basel)
January 2025
State Key Laboratory of Coal Mine Disasters Dynamics and Control, Chongqing University, Chongqing 400044, China.
To investigate the mechanical and energy evolution characteristics of fractured rock under true triaxial stresses, true triaxial strength compression experiments on fractured sandstone were conducted with varying crack lengths and widths. The results indicate that under true triaxial stresses, the peak stress of the rock exhibits a gradual decline with an increase in crack length and width. Meanwhile, crack initiation stress and crack damage stress of fractured sandstone also demonstrate a declining trend overall, and the influence of crack length on the characteristic stress (crack initiation stress and crack damage stress) of sandstone is more pronounced than that of crack width.
View Article and Find Full Text PDFAssociations of resuscitation fluid load, colloid-to-crystalloid infusion ratio and clinical outcomes in children with dengue shock syndrome.
PLoS Negl Trop Dis
January 2025
Department of Infectious Diseases, Children's Hospital 2, Ho Chi Minh City, Vietnam.
Background: Severe respiratory distress and acute kidney injury (AKI) are key factors leading to poor outcomes in patients with dengue shock syndrome (DSS). There is still limited data on how much resuscitated fluid and the specific ratios of intravenous fluid types contribute to the development of severe respiratory distress necessitating mechanical ventilation (MV) and AKI in children with DSS.
Methodology/principal Findings: This retrospective study was conducted at a tertiary pediatric hospital in Vietnam between 2013 and 2022.
Are quality-adjusted life years (QALYs) becoming more expensive? Evidence from economic evaluations of diabetic therapeutics.
Expert Rev Pharmacoecon Outcomes Res
January 2025
School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, China.
Background: Empirical evidence regarding temporal trends in cost per quality-adjusted life year (QALY) gained remains limited. This study investigates the evolution of cost-effectiveness for diabetes mellitus treatments over time.
Research Design And Methods: We analyzed cost-effectiveness analyses of anti-diabetic pharmaceuticals extracted from the Tufts Medical Center Cost-Effectiveness Analysis Registry (CEAR).
Phenobarbital toxicosis in a pied butcherbird, Cracticus nigrogularis.
Aust Vet J
January 2025
Currumbin Wildlife Sanctuary Hospital, Currumbin, Queensland, Australia.
A wild, adult male pied butcherbird (Cracticus nigrogularis) accidentally ingested 263 mg/kg of oral phenobarbital. Pronounced sedation was observed by 30 mins, followed by altered consciousness, marked ataxia and increased respiratory effort. The serum phenobarbital level on admission to a wildlife hospital was 84.
View Article and Find Full Text PDFTechnological innovation of HoLEP: a multicenter, randomized, controlled study for the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia.
World J Urol
January 2025
Department of Urology, Zhangjiagang Hospital Affiliated to Soochow University, Suzhou, Jiangsu, China.
Purpose: The purpose of this study was to investigate the efficacy of Transurethral Holmium Laser of the Prostate (HoLEP) with Double-n Technology in the treatment of benign prostatic hyperplasia (BPH), with a focus on preserving sexual function postoperatively.
Methods: Conducted as a multicenter, prospective, single-blind randomized controlled trial, this study enrolled sexually active male patients with BPH. Participants were randomized into three groups: standard HoLEP (Group A), single-n technology (Group B), and innovative double-n technology (Group C), which emphasizes the preservation of the urethral mucosa and nearby structures.
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