Purpose: To evaluate treatment options for candida keratitis and endopthalmitis after corneal transplantation.

Methods: Case reports and literature review.

Results: Two patients with keratitis due to / after corneal transplantation were successfully treated with a combination of topical voriconazole, intracameral voriconazole and amphotericin B, and systemic treatment with flucytosine.

Conclusions: Natamycine and voriconazole topically are preferred therapeutic options for the treatment of fungal keratitis. Systemic flucytosine is a useful alternative additive, particularly for countries where natamycine is not registered as a pharmaceutical agent.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999277PMC
http://dx.doi.org/10.1177/11206721211060140DOI Listing

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