We synthesized critical evidence regarding causal inferences of Adverse Childhood Experience (ACE) exposure and subsequent disease development. Extensive and high-quality research supports causal inferencing and offers a solid ground for policy- and decision-makers interested in translating science into societal action. There is ample evidence supporting system-wide implementation of prevention and treatment even though research on mechanisms needs to and will continue to offer additional insights.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/jcpp.13541 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Bayesian Sequential Pragmatic Cluster Randomized Clinical Trial Design for PrEventive Effect of MEditerranean Diet in Children: PEMED Trial Research Protocol.
J Clin Med
January 2025
European Laboratory for Food Induced Diseases, University of Naples Federico II, 80131 Naples, Italy.
Childhood nutrition plays an important role in the promotion of long-term health. Introducing solid foods in alignment with the Mediterranean Diet during weaning fosters a preference for healthy foods early in life. However, access to nutritious diets remains a challenge in underserved communities.
View Article and Find Full Text PDFBreastfeeding Practices and Food Consumption of Socially Vulnerable Children.
Foods
January 2025
Graduate Program in Public Health, Faculty of Health Sciences, University of Brasília, Brasília 70910-900, DF, Brazil.
Promoting child well-being and development requires a multidimensional approach, including the right to adequate food practices. Socially vulnerable children are more exposed to adverse experiences, such as inadequate food consumption due to poverty. In this context, home-visiting programs are an important strategy for nutritional and health care education to provide relevant guidelines.
View Article and Find Full Text PDFLentivirus-mediated gene therapy for Fabry disease: 5-year End-of-Study results from the Canadian FACTs trial.
Clin Transl Med
January 2025
Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Background: Fabry disease is an X-linked lysosomal storage disorder due to a deficiency of α-galactosidase A (α-gal A) activity. Our goal was to correct the enzyme deficiency in Fabry patients by transferring the cDNA for α-gal A into their CD34+ hematopoietic stem/progenitor cells (HSPCs). Overexpression of α-gal A leads to secretion of the hydrolase; which can be taken up and used by uncorrected bystander cells.
View Article and Find Full Text PDFTypological and cumulative approaches to risk and adversity in Child and Adolescent Mental Health Services (CAMHS): Retrospective cohort analysis in South London.
Compr Psychiatry
December 2024
Department of Public Health and Primary Care, University of Cambridge, UK. Electronic address:
Background: Childhood adversity is robustly associated with mental ill-health. Yet questions remain about how different ways of conceptualising adversity relate to psychiatric diagnoses and service activity. This research aims to examine associations between typological and cumulative conceptualisations of adversity, and psychiatric diagnosis and service activity.
View Article and Find Full Text PDFHigher population density is associated with worse air quality and related health outcomes in Tāmaki Makaurau.
Aust N Z J Public Health
January 2025
Department of Epidemiology and Biostatistics, University of Auckland, New Zealand.
Objectives: To explore associations between population density, air pollution concentrations, and related health outcomes in Tāmaki Makaurau Auckland, Aotearoa New Zealand.
Methods: Concentrations of nitrogen dioxide (NO) and fine particulate matter (PM) and associated health outcomes (premature mortality, cardiovascular and respiratory hospitalisations, and childhood asthma) were obtained from the Health and Air Pollution in New Zealand 2016 study. The possible mediating factors assessed were motor vehicle traffic, domestic fires, local industry, and green space.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!