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Intracranial Myeloid Sarcoma Arising Intra-axially From Acute Myeloid Leukemia: A Case Report and Literature Review.
Cureus
August 2024
Department of Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya, JPN.
Article Synopsis
- * Imaging revealed a mass in the right cerebellum, and subsequent surgical resection showed the tumor's characteristics included small round cells and signs of macrophage invasion, highlighting its connection to the AML.
- * The case emphasizes the importance of considering intracranial myeloid sarcoma in patients with a history of hematological cancers like AML, despite challenges in differentiating tumor types through imaging.
Isolated recurrence of acute myeloid leukemia in the cerebellum: illustrative case.
J Neurosurg Case Lessons
August 2021
Department of Neurosurgery, Dell Medical School, The University of Texas at Austin, Austin, Texas; and.
Background: Myeloid sarcoma is a rare malignant hematopoietic neoplasm that arises at extramedullary sites. Although myeloid sarcoma may involve any organ, central nervous system (CNS) involvement is exceptionally rare. To date, few case reports and case series have described CNS myeloid sarcoma, the majority of which include peripheral disease.
View Article and Find Full Text PDFTreatment Outcomes of Intracranial Myeloid Sarcomas: A Meta-Analysis.
World Neurosurg
April 2021
Department of Neurological Surgery, University of California, Davis, California, USA. Electronic address:
Objective: Intracranial myeloid sarcomas (IMS) are rare central nervous system manifestations of malignant hematopoietic neoplasms of myeloid origin such as acute myeloid leukemia and chronic myeloid leukemia. Reported cases in the literature are limited to primarily case reports. We present a systematic review of this rare central nervous system tumor, characterizing the clinical presentation, tumor location, histopathology, and available treatment modalities.
View Article and Find Full Text PDFMyeloid sarcoma: a report of four cases at unusual sites.
Ger Med Sci
May 2018
JLNM Hospital, Srinagar, India.
Myeloid sarcoma (MS) or granulocytic sarcoma is a rare tumor consisting of myeloid blasts with or without maturation occurring at anatomic sites other than the bone marrow. MS can involve any organ system but shows a predilection for skin, bone, and soft tissues of head and neck region. We report four cases of MS occurring at unusual sites, out of which three were de novo and one was associated with acute myeloid leukemia (AML).
View Article and Find Full Text PDFGene methylation in gastric cancer.
Clin Chim Acta
September 2013
Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University School of Medicine, Xi'an 710061, People's Republic of China.
Gastric cancer is one of the most common malignancies and remains the second leading cause of cancer-related death worldwide. Over 70% of new cases and deaths occur in developing countries. In the early years of the molecular biology revolution, cancer research mainly focuses on genetic alterations, including gastric cancer.
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