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http://dx.doi.org/10.1016/j.jaad.2021.11.015 | DOI Listing |
J Ultrasound Med
December 2024
AST Ancona, Ospedale di Comunità Maria Montessori di Chiaravalle, Ancona, Italy.
JAAD Int
February 2025
Department of Dermatology, University of California, San Francisco, California.
Eur J Med Res
December 2024
Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, No. 7 Weiwu, Zhengzhou, 450003, Henan, China.
Background: Nicastrin, a subunit of the γ-secretase complex, is encoded by the NCSTN gene and regulates notch signaling, it is involved in the pathogenesis of hidradenitis suppurativa (HS), Alzheimer disease (AD), and liver cancer. However, the animal models for studying HS are relatively scarce.
Methods: CRISPR/Cas-mediated genetic engineering was used to generate targeted knockout offspring mice (C57BL/6J).
Dermatology
December 2024
Department of Dermatology, Zealand University Hospital, Roskilde, Denmark.
Background: Hidradenitis suppurativa (HS), a chronic inflammatory skin disease affecting intertriginous areas, presents a recurring and debilitating challenge. Even though recent efforts have been made to estimate the overall HS prevalence, variations in screening modalities and missing data from the Global South warrant further investigation. Understanding the HS prevalence is crucial for treatment approaches and pathogenesis.
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