Imaging Cognitive Impairment and Impulse Control Disorders in Parkinson's Disease.

Front Neurol

Department of Neurology, Clínica Universidad de Navarra, Pamplona, Spain.

Published: November 2021

Dementia and mild forms of cognitive impairment as well as neuropsychiatric symptoms (i. e., impulse control disorders) are frequent and disabling non-motor symptoms of Parkinson's disease (PD). The identification of changes in neuroimaging studies for the early diagnosis and monitoring of the cognitive and neuropsychiatric symptoms associated with Parkinson's disease, as well as their pathophysiological understanding, are critical for the development of an optimal therapeutic approach. In the current literature review, we present an update on the latest structural and functional neuroimaging findings, including high magnetic field resonance and radionuclide imaging, assessing cognitive dysfunction and impulse control disorders in PD.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602579PMC
http://dx.doi.org/10.3389/fneur.2021.733570DOI Listing

Publication Analysis

Top Keywords

impulse control
12
control disorders
12
parkinson's disease
12
cognitive impairment
8
neuropsychiatric symptoms
8
imaging cognitive
4
impairment impulse
4
disorders parkinson's
4
disease dementia
4
dementia mild
4

Similar Publications

Seasonal effect of PM exposure in patients with COPD: a multicentre panel study.

Environ Sci Process Impacts

January 2025

Department of Pulmonary and Critical Care Medicine, Clinical Research Center for Chronic Obstructive Airway Diseases, University of Ulsan College of Medicine, Asan Medical Center, 88, Olympic-ro 43-Gil, Songpa-gu, Seoul 05505, South Korea.

: Exposure to particulate matter <2.5 μm (PM) is linked to chronic obstructive pulmonary disease (COPD), but most studies lack individual PM measurements. Seasonal variation and their impact on clinical outcomes remain understudied.

View Article and Find Full Text PDF

Externalizing traits and behaviors are broadly defined by impairments in self-regulation and impulse control that typically begin in childhood and adolescence. Externalizing behaviors, traits, and symptoms span a range of traditional psychiatric diagnostic categories. In this study, we sought to generate an algorithm that could reliably identify transdiagnostic childhood-onset externalizing cases and controls within a university hospital electronic health record (EHR) database.

View Article and Find Full Text PDF

Previous research has found functional connectivity in various networks to be altered in psychopathy and has theorised a link between these networks and the self-control-related deficits observed in psychopathy. However, this theory has yet to be tested adequately and empirically. The present study investigated the association between psychopathy, self-control, and intrinsic functional connectivity in 179 healthy adults from the MPI Leipzig Mind Brain Body dataset.

View Article and Find Full Text PDF

The application of a pulsed magnetic field (PMF) during a metallurgy solidification process has proven to be an effective method in refining the grain size and improving the mechanical performance of the material. However, fewer works were reported in the realm of laser additive manufacturing (LAM) and the mechanism of grain refinement consequent to the PMF is still unclear. In this work, numerical models were developed to study the thermal-fluid characteristics in the Ti-alloy melt pool generated during the laser scanning process under the effect of a combined direct current (DC) electric field and PMF.

View Article and Find Full Text PDF

In this paper, we propose an epidemic mathematical model with an impulsive vaccination strategy to predict outbreaks in chickens caused by vectors. The analysis of the model is divided into two parts: one considering impulsive vaccination and the other without it. We determine the basic reproduction number of disease transmission and analyze the stability conditions of the proposed model for both disease-free and endemic equilibria, addressing both local and global stability.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!