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Clinical Characteristics of Coronavirus Disease 2019 (COVID-19): A Comparison Between Laboratory-Confirmed and Clinically Suspected Patients. | LitMetric

Clinical Characteristics of Coronavirus Disease 2019 (COVID-19): A Comparison Between Laboratory-Confirmed and Clinically Suspected Patients.

Iran J Sci Technol Trans A Sci

Teaching and Research Section of Clinical Nursing, Xiangya Hospital of Central South University, No. 87 Xiangya Road, Changsha, 410008 Hunan China.

Published: November 2021

AI Article Synopsis

  • The study aimed to compare findings between laboratory-confirmed COVID-19 patients and those clinically suspected of having the virus, analyzing data from 241 patients admitted to Xiangya Hospital from January to February 2020.
  • A higher prevalence of COVID-19 was found in males (64.3%) compared to females (35.7%), with common symptoms including fever and cough prior to admission.
  • The confirmed patients frequently had a history of exposure to high-risk areas (71.4%) and displayed specific pulmonary imaging findings, such as ground-glass opacity, highlighting the importance of epidemiological history and nucleic acid testing in distinguishing between confirmed and suspected cases.

Article Abstract

To investigate the characteristic findings between laboratory-confirmed and clinically suspected patients with COVID-19. In this retrospective study, we included patients admitted to the Xiangya Hospital from Jan 24 to Feb 10, 2020. Two researchers separately collected and sorted out the patients' epidemiological, demographic, clinical, laboratory, and radiologic findings. SPSS was performed to analyze the collected data. 241 patients were admitted, including 28 (45.5; IQR, 34.0-52.5) confirmed and 213 (42.0; IQR, 30.0-57.0) suspected patients. The prevalence of COVID-19 disease in males was significantly higher than in females (64.3% vs. 35.7%,  = 0.033). Before admission of the confirmed and suspected undiagnosed cases, the onset of symptoms is often manifested as respiratory symptoms such as fever (35.7% vs. 27.7%) and cough (30.7% vs. 32.1%). Twenty patients (71.4%) had an exposure history to high-risk areas, and 14 patients (50.0%) traveled or lived in a high-risk area in the confirmed group, which was significantly different from the suspected group. The pulmonary imaging of the patients in the confirmed group was primarily manifested as ground-glass opacity (89.3%). A total of 499 nucleic acid testing (NAT) was performed to determine the 28 COVID-19 positive throat swabs among the 241 patients. Whether there is a history of high-risk area exposure in the epidemiological investigation is essential in distinguishing the suspected patients from the confirmed patients. Multiple nucleic acid tests were used as the basis for the diagnosis of COVID-19, and during CT examination, ground-glass opacity was used as a COVID-19 indicator. Trail registration number. 202012195, Date of registration: 2020.12.22 "retrospectively registered".

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590879PMC
http://dx.doi.org/10.1007/s40995-021-01244-8DOI Listing

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