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A Systematic Review of Indocyanine Green Lymphography (ICGL) Imaging for the Diagnosis of Primary Lymphoedema.
Br J Radiol
January 2025
School of Health & Medical Sciences, City St George's, University of London, London, SW17 0RE, UK.
Objectives: This systematic review aims to evaluate the use of Indocyanine Green Lymphography (ICGL) for the investigation of the lymphatics in the lower limbs of primary lymphoedema patients.
Methods: MEDLINE and EMBASE articles from 01/01/2000 to 01/09/2023 were searched for. A total of 11 studies were included in the review after a two-stage screening process.
Interventional solutions for post-surgical problems: a lymphatic leaks review.
CVIR Endovasc
August 2024
Biomedical Imaging Research Group (GIBI2^30), La Fe Health Research Institute (IIS La Fe), Avenida Fernando Abril Martorell, València, 46026, Spain.
The lymphatic circulation plays a crucial role in maintaining fluid balance and supporting immune responses by returning serum proteins and lipids to the systemic circulation. Lymphatic leaks, though rare, pose significant challenges post-radical neck surgery, oesophagectomy, and thoracic or retroperitoneal oncological resections, leading to heightened morbidity and mortality. Managing lymphatic leaks necessitates consideration of aetiology, severity, and volume of leakage.
View Article and Find Full Text PDFLymphaticovenous anastomosis in rabbits: A novel live experimental animal model for supermicrosurgical training.
J Plast Reconstr Aesthet Surg
June 2024
Department of Plastic Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Background: Lymphaticovenous anastomosis is widely used in lymphedema management. Although its effectiveness in reducing edema in patients can be clinically observed, evaluating the long-term outcomes of this technique can be complex. This study established an animal model to assess the outcomes of lymphaticovenous anastomosis technique at 15 and 30-days post-surgery using indocyanine green lymphography, Patent Blue V dye injection, and histopathological examination.
View Article and Find Full Text PDFSentinel node restoration by vascularized lymph node transfer in mice.
Microsurgery
January 2024
Department of Plastic and Reconstructive Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Background: Recent reports have indicated that vascularized lymph node transfer (VLNT) may improve the impaired immunity in lymphedema but there has been no report concerning anti-cancer immunity. In the early tumor immune response, dendritic cells (DCs) participate in tumor recognition and antigen presentation in local lymphatics. Here, we investigated the impact of VLNT on DC dynamics against cancer in mouse models.
View Article and Find Full Text PDFDetection and differentiation of semi-transparent materials simulating biological structures using optical coherence tomography: a phantom study.
J Biomed Opt
October 2022
Princess Margaret Cancer Centre, Division of Biophysics and Bioimaging, Toronto, Ontario, Canada, Canada.
Significance: Lymphatic and peripheral nervous system imaging is of prime importance for monitoring various important pathologic processes including cancer development and metastasis, and response to therapy.
Aim: Optical coherence tomography (OCT) is a promising approach for this imaging task but is challenged by the near-transparent nature of these structures. Our aim is to detect and differentiate semi-transparent materials using OCT texture analysis, toward label-free neurography and lymphography.
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