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Hallmarks of Appetite: A Comprehensive Review of Hunger, Appetite, Satiation, and Satiety.
Curr Obes Rep
January 2025
CRO Aviano, National Cancer Institute, IRCCS, Aviano, Italy.
Purpose Of Review: The present review describes the available literature on the physiologic mechanisms that modulate hunger, appetite, satiation, and satiety with a particular focus on well-established and emerging factors involved in the classic satiety cascade model.
Recent Finding: Obesity is a significant risk factor for numerous chronic conditions like cancer, cardiovascular diseases, and diabetes. As excess energy intake is considered by some to be the primary driver of weight gain, tremendous collective effort should be directed toward reducing excessive feeding at the individual and population levels.
Pharmacokinetics of Nivolumab and Erythropoietin in a Rat Model of Diet-Induced Obesity.
Pharm Res
January 2025
Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ, 08854, USA.
Purpose: To investigate how obesity affects the pharmacokinetics of biologics in a rat model.
Method: Male Long-Evans rats were fed a high-fat diet from the age of 3 weeks and development of obesity was monitored by measuring body size and composition (fat and lean mass). The animals received nivolumab (1 and 8 mg/kg) or recombinant human erythropoietin (rHuEPO, 1000 IU/kg) by intravenous or subcutaneous injection.
Impact of monensin, virginiamycin, trace minerals, and yeast combination on animal performance, carcass and meat characteristics of finishing feedlot bulls fed high grain diet.
Trop Anim Health Prod
January 2025
Department of Animal Science, Universidade Estadual de Maringá, Av. Colombo, 5790, Maringá, Paraná, 87020-900, Brazil.
This study was realized to evaluate the influence of monensin, virginiamycin,trace minerals and yeast combination on animal performance, feed efficiency, in situ digestibility, feeding behavior, and carcass and meat characteristics from bulls finished in feedlot fed high-grain diet. A total of 36 (European vs. Nellore) bulls at 24 ± 3.
View Article and Find Full Text PDFCapturing food insecurity data and implications for business and policy.
Proc Nutr Soc
January 2025
Ulster University Business School, Ulster University, Cromore Road, Coleraine, Northern Ireland 028 7012 3964).
Food insecurity (also known as food poverty) is the inability to afford or access a healthy diet. It has become recognised as a public health emergency and is a priority in the context of the environmental, geopolitical and socio-economic implications on businesses, households and civic society. This review paper aims to discuss the merits of collecting food insecurity data and its importance in informing cross-sectoral government and others' understanding, policymaking and action on hunger.
View Article and Find Full Text PDFSupermarkets, do they make the healthy choice the easy choice? A review of the healthfulness of the supermarket food environment.
Proc Nutr Soc
January 2025
College of Business, UCD, Belfield, Dublin 4, Ireland.
The over consumption of high fat, sugar, and salt foods increases population risk of overweight, obesity and diet-related noncommunicable diseases. The food environment mediates consumer food choices and thus plays an important role in diet quality and related health outcomes. The built food environment, where most people in high income countries access their food, has been found to be obesogenic.
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