Shi et al. (2021) demonstrate that tumor-suppressive and developmental functions of UTX require an intrinsically disordered region (IDR) capable of condensate formation. These results provide further evidence for the functional role of IDR-mediated spatial organization in regulating gene expression in development and disease.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.molcel.2021.10.021 | DOI Listing |
Publication Analysis
Top Keywords
disordered dead
4
dead good
4
good company
4
company catalytically
4
catalytically inactive
4
inactive utx
4
utx retains
4
retains function
4
function shi
4
shi et al
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!