Functional analyses allow clinicians to develop treatment targeting the variables maintaining a child's inappropriate mealtime behavior (Bachmeyer et al., 2019). Extended functional analyses can be inefficient, potentially delaying the onset of treatment. Researchers have suggested a trial-based functional analysis can increase assessment efficiency (Saini, Fisher, et al., 2019). This study compared trial-based functional analyses to extended functional analyses to determine the variables maintaining inappropriate mealtime behavior. We compared the efficiency and acceptability and evaluated treatments informed by the analyses. Exact correspondence between analyses was low (29%); however, most treatments indicated by the trial-based functional analyses (80%) resulted in improvements in the child's target behavior. The trial-based functional analysis required 71% less time than the extended functional analysis, and caregivers found analyses equally acceptable. Future researchers should continue refining trial-based functional analysis procedures to provide an efficient assessment that leads to efficacious treatment.
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http://dx.doi.org/10.1002/jaba.888 | DOI Listing |
J Funct Morphol Kinesiol
October 2024
Conahcyt National Laboratory of Body Composition and Energetic Metabolism (LaNCoCoME), Tijuana 22390, Mexico.
Exercise is an essential pillar for human health, as it contributes to physical, mental, and emotional well-being. Well-recognized international organizations, such as the World Health Organization, advocate for integrating exercise into healthy lifestyles, recognizing its importance in disease prevention and improving quality of life. However, despite the consensus on its value, there is no universal agreement on specific prescriptions for vulnerable groups, highlighting the need for personalized approaches that consider the unique characteristics and needs of everyone.
View Article and Find Full Text PDFAnimal
December 2024
Department of Agronomy, Food, Natural Resources, Animals and Environment (DAFNAE), University of Padova, Viale dell'Università 16, 35020 Legnaro, Padova, Italy.
The inclusion of microalgae in livestock diets has been shown to enhance animal productivity, immune response, and meat quality. However, the role of chlorella (Chlorella vulgaris) in growing rabbit nutrition has been scarcely explored, with available studies focusing on low inclusion levels (<1%) and their effects on rabbit growth and immune response. This study evaluated the growth performance, nutrient digestibility, plasma metabolites, caecal fermentative activity, and caecal microbiota composition of growing rabbits fed diets with different inclusion levels of chlorella and crude fat.
View Article and Find Full Text PDFJ Natl Cancer Inst Monogr
November 2024
Center for Health Decision Science, Department of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Background: A concern in high-income countries is that switching to 1-dose human papillomavirus (HPV) vaccination could cause a rebound in HPV infection and cervical cancer if 1-dose efficacy or duration were inferior to 2 doses. Using mathematical modeling and up-to-date trial-based data, we projected the population-level effectiveness of switching from 2-dose to 1-dose vaccination under different vaccine efficacy and duration assumptions in high-income countries.
Methods: We used HPV-ADVISE (Agent-based Dynamic model for VaccInation and Screening Evaluation), a transmission-dynamic model of HPV infection and cervical cancer, varying key model assumptions to identify those with the greatest impact on projections of HPV-16 and cervical cancer incidence over time: 1) 1-dose vaccine efficacy and vaccine duration, 2) mechanisms of vaccine efficacy and duration over time, 3) midadult (>30 years of age) sexual behavior, 4) progression to cervical cancer among midadults, and 5) vaccination coverage and programs.
Mol Psychiatry
November 2024
Research Cluster Molecular and Cognitive Neurosciences, Department of Biomedicine, University of Basel, CH-4055, Basel, Switzerland.
Working memory (WM), a key component of cognitive functions, is often impaired in psychiatric disorders such as schizophrenia. Through a genome-guided drug repurposing approach, we identified fampridine, a potassium channel blocker used to improve walking in multiple sclerosis, as a candidate for modulating WM. In a subsequent double-blind, randomized, placebo-controlled, crossover trial in 43 healthy young adults (ClinicalTrials.
View Article and Find Full Text PDFJ Appl Behav Anal
November 2024
Department of Applied Behavioral Science, University of Kansas, Lawrence, Kansas, USA.
Functional analyses are used to assess maintaining variables of behavior. Despite the large amount of research on functional analyses with humans, there are limited examples with nonhumans and even fewer studies incorporating modifications to standard methods of assessment with nonhumans. One modification that has yet to be evaluated with nonhuman animals is the trial-based functional analysis in which control and test conditions are embedded in naturalistic environments.
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