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Non-episodic angioedema with eosinophilia as a differential diagnosis of eosinophilia in young females.
World Allergy Organ J
November 2024
Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Background: Episodic angioedema with eosinophilia, also known as Gleich's syndrome, is a differential diagnosis in patients with recurrent angioedema with higher blood eosinophils. Meanwhile, less has been elucidated regarding non-episodic angioedema with eosinophilia (NEAE). This study aimed to examine the prevalence, clinical characteristics, and disease course of NEAE.
View Article and Find Full Text PDFNonepisodic angioedema with eosinophilia subsequent to acute parvovirus B19 infection.
BMJ Case Rep
September 2024
General Internal Medicine, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan
Article Synopsis
- Nonepisodic angioedema with eosinophilia (NEAE) is identified by localized swelling in the limbs and an increase in eosinophils in the blood.
- A rare case is reported where a young woman developed NEAE during an acute B19 virus infection, experiencing itching, joint pain, and swelling in her extremities.
- The symptoms improved with a short course of prednisolone, and she has been symptom-free for over two years, suggesting a connection between NEAE and B19 infection.
Nonepisodic angioedema with eosinophilia following a rose-thorn prick injury.
Int J Cardiol Cardiovasc Risk Prev
September 2024
Department of Respiratory Medicine, Tokyo Shinagawa Hospital, Shinagawa-ku, Tokyo, Japan.
Background: Nonepisodic angioedema with eosinophilia (NEAE) is a condition marked by angioedema and significant eosinophilia and often linked with atopic dermatitis. It predominantly affects young Asian women and occurs more frequently in the autumn and winter. Despite over 100 reported cases, its etiology and pathogenesis remain unclear.
View Article and Find Full Text PDFSafe re-immunization of mRNA-1273 COVID-19 vaccine after BNT162b2 mRNA COVID-19 vaccine-induced nonepisodic angioedema with eosinophilia.
Postgrad Med J
September 2024
Department of Medicine, Samitivej Sukhumvit Hospital, Bangkok, 10110, Thailand.
Nonepisodic Angioedema with Eosinophilia Following Receipt of the BNT162b2 mRNA COVID-19 Vaccine.
Intern Med
October 2023
Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Japan.
Angioedema with eosinophilia (AE) is a rare disease of unknown etiology characterized by episodic (EAE) or nonepisodic AE (NEAE). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA-based vaccines function as immunogens and intrinsic adjuvants and have been shown to be safe in large-scale trials. However, the long-term adverse reactions, especially those related to eosinophilic complications, have not been fully clarified.
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