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| http://dx.doi.org/10.1016/j.bjorl.2021.08.009 | DOI Listing |
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Misconceptions about paraoxonase-1.
Braz J Otorhinolaryngol
February 2022
Ege University Faculty of Medicine, Department of Medical Biochemistry, Bornova, Turkey.
Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma.
Biochem Pharmacol
November 2005
University of Nebraska Medical Center, Eppley Institute, Omaha, NE 68198-6805, USA.
Article Synopsis
- The study aimed to identify esterases in human plasma and clear up common misconceptions about them.
- Human plasma contains four types of esterases: butyrylcholinesterase (BChE), paraoxonase (PON1), acetylcholinesterase (AChE), and albumin, with BChE, PON1, and albumin contributing significantly to ester hydrolysis.
- The research debunks two misconceptions: first, human plasma does not contain carboxylesterase, and second, lab animals do have substantial amounts of AChE in addition to BChE, unlike humans.
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