Objective: To investigate whether HALP score [hemoglobin, albumin, lymphocyte (LY), platelet] can predict weight loss in patients undergoing sleeve gastrectomy.
Study Design: A cohort study.
Place And Duration Of Study: Department of General Surgery, Balıkesir University, Turkey from July 2019 to July 2020.
Methodology: One-year data of 64 patients, who underwent sleeve gastrectomy due to obesity were included for the analysis. The cut-off value of HALP score was calculated to be 41.2971. Those below the cut-off value were classified into Group 1 (low HALP score) and those above it were classified into Group 2 (high HALP score). Preoperative and postoperative body mass index (BMI), hemotologic parameters, platelet/LY ratios (PLR), and neutrophil/LY ratios (NLR), were compared. According to the percentage of excess BMI loss, patients were divided into 3 groups: Group A (≤40%), Group B (40%-60%), Group C (≥60%).
Results: The decrease in postoperative BMI was significantly high in Group 2 (p<0.001). There was a significant difference between the groups in terms of percentage change of hemoglobin (p=0.012). The increase in postoperative LY value and decrease in postoperative PLR value were significantly high in Group 1 (p=0.019, p=0.003). Furthermore, patient distribution was significantly different among groups A, B, and C (p <0.001). Comparison of groups showed a significant difference between groups A and B and between groups A and C, but not between groups B and C (p=0.006, p<0.001, and p=0.192, respectively).
Conclusion: In patients with high HALP scores, the rate of weight loss was higher, and most of their laboratory parameters were improved compared to those patients with low HALP scores. Key Words: Body mass index, Sleeve gastrectomy, obesity, Weight loss, HAIP score.
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http://dx.doi.org/10.29271/jcpsp.2021.12.1406 | DOI Listing |
Front Immunol
January 2025
Department of Urology, People's Hospital of Deyang City, Chengdu University of Traditional Chinese Medicine, Deyang, China.
Objective: The high hemoglobin, albumin, lymphocyte, and platelet (HALP) score has been reported to be a good prognostic indicator for several malignancies. However, more evidence is needed before it can be introduced into clinical practice. Here, we systematically evaluated the predictive value of HALP for survival outcomes in patients with solid tumors.
View Article and Find Full Text PDFPeerJ
December 2024
Department of Oncology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Background: Recent studies have revealed that inflammatory factors and nutritional status of patients with advanced gastric cancer (AGC) are related to the efficacy of drug therapy and patient prognosis. This study seeks to evaluate the correlation between inflammatory markers, nutritional status, and clinical outcomes of immune checkpoint inhibitor (ICI)-based therapies among inoperable AGC patients.
Method: This retrospective study included 88 AGC patients who received ICIs combined with chemotherapy.
Int J Urol
December 2024
Scientific Centre of Excellence for Reproductive and Regenerative Medicine, School of Medicine, University of Zagreb, Zagreb, Croatia.
Front Oncol
December 2024
Division of Medical Oncology, Department of Internal Medicine, Trakya University School of Medicine, Edirne, Türkiye.
J Clin Med
November 2024
Department of Obstetrics and Gynecology, Health Sciences University Etlik Zubeyde Hanim Maternity, Teaching and Research Hospital, 06010 Ankara, Turkey.
: In this study, the aim was to investigate blood-based clinical biomarkers of inflammation and nutrition indices in hyperemesis gravidarum (HG). : This retrospective case-control study was conducted at a tertiary hospital between 2018 and 2022. A total of 820 pregnant women were enrolled in this study; 410 pregnant women were diagnosed with HG (HG group) at 6-14 weeks of gestation, and 410 pregnant women were healthy controls (control group) in the same gestational weeks.
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