In this study 411 bacterial isolates from clinical urinary tract infections against some quinolones, azthreonam and trimethoprim + sulfamethoxazole combination were tested. Bactericidal kinetics of norfloxacin , cinoxacin and azthreonam against E. coli ATCC 25922 was determined. Both MICs values and bactericidal activities have shown that fluoroquinolones are more active against all Gram-positive and Gram-negative bacteria tested than the other drugs.
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