AI Article Synopsis
- - The study compared causes of death in non-ST-segment-elevation myocardial infarction (NSTEMI) and ST-segment elevation myocardial infarction (STEMI) patients, involving over 6,000 heart attack cases.
- - Results showed no significant difference in overall mortality risk between NSTEMI and STEMI patients both within and after 6 months of their incident, although specific causes of death varied between the two groups during the first 6 months.
- - The findings suggest that while NSTEMI patients had more deaths from heart failure and post resuscitation status shortly after a heart attack, the long-term risk of death was similar for both types of patients.
Article Abstract
Background: The detailed causes of death in non-ST-segment-elevation myocardial infarction (NSTEMI) have not been adequately evaluated compared to those in ST-segment elevation myocardial infarction (STEMI).
Methods: The study population was 6,228 AMI patients who underwent percutaneous coronary intervention (STEMI: 4,625 patients and NSTEMI: 1,603 patients). The primary outcome was all-cause death.
Results: Within 6 months after AMI, the adjusted mortality risk was not significantly different between NSTEMI patients and STEMI patients (HR: 0.83, 95%CI: 0.67-1.03, P = 0.09). Regarding the causes of death within 6 months after AMI, mechanical complications more frequently occurred in STEMI patients than in NSTEMI patients, while proportions of post resuscitation status on arrival and heart failure were higher in in NSTEMI patients than in STEMI patients. Beyond 6 months after AMI, the adjusted mortality risk of NSTEMI relative to STEMI was not significantly different. (HR: 1.04, 95%CI: 0.90-1.20, P = 0.59). Regarding causes of death beyond 6 months after AMI, almost half of deaths were cardiovascular causes in both groups, and breakdown of causes of death was similar between NSTEMI and STEMI.
Conclusion: The mortality risk within and beyond 6 months after AMI were not significantly different between STEMI patients and NSTEMI patients after adjusting confounders. Deaths due to post resuscitation status and heart failure were more frequent in NSTEMI within 6 months after AMI.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598015 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0259268 | PLOS |
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