Particular tumor of the pancreas: A case report.

World J Clin Cases

Department of Hepatopancreatobiliary Surgery, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, Henan Province, China.

Published: October 2021

AI Article Synopsis

  • Granular cell tumor (GCT) of the pancreas is a rare type of neurogenic tumor, with only 7 cases reported since its first identification in 1975.
  • A 53-year-old male presented with a pancreatic mass, which was confirmed to be GCT through imaging and microscopic analysis showing specific cell markers.
  • It is essential to consider GCT in the diagnosis of pancreatic tumors, and while surgical removal is recommended, long-term follow-up is necessary due to potential metastasis and recurrence.

Article Abstract

Background: Granular cell tumor (GCT) of the pancreas is a rare neurogenic tumor. The first case of pancreatic GCT was described in 1975, and up to now, only 7 cases have been reported.

Case Summary: A 53-year-old male had a pancreatic mass for 1 mo. He was not treated at the local hospital, but referred to Henan Tumor Hospital for surgery. Preoperative imaging revealed a 2.0 cm × 2.5 cm-sized mass located in the body of the pancreas. At the microscopic level, a large number of eosinophilic particles are present in the oval tumor cells. The immunohistochemistry of this tumor cell display CD56 (+), blood vessels CD34 (+), Ki-67 (+) < 10%, and S-100 (+).

Conclusion: GCT of the pancreas should be recognized as a preoperative differential diagnosis of pancreatic tumors. Surgical resection of the tumor should be attempted; however, GCT of the pancreas has a certain rate of tumor metastasis and recurrence. Therefore, GCT of the pancreas requires regular and long-term follow-up.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567512PMC
http://dx.doi.org/10.12998/wjcc.v9.i30.9101DOI Listing

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