Water has numerous functions necessary for survival including cellular homeostasis, solvent properties for dissolving ions and solutes, thermoregulation, and transport of waste and nutrients. Despite the established beneficial role of water in skin physiology, the optimal methods for skin hydration and requirements for daily water consumption remain elusive. This review summarizes the cellular and molecular biology of skin hydration, the debate and current recommendations of daily water requirements, and the latest research on interventions to improve skin hydration by both internal and external means of water exposure. We also explore the chemical properties of water, such as the concept of water "hardness" and environmental pollutants, and their impact on skin physiology.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.clindermatol.2021.05.003 | DOI Listing |
Metabolites
January 2025
Medical Department, Cantabria Labs Difa Cooper, 21042 Caronno Pertusella, Italy.
This study aimed to evaluate the efficacy of a novel "In & Out" strategy, combining topical and oral melatonin supplementation, in managing skin aging compared to topical treatment alone. A randomized, prospective study was conducted on 39 healthy females aged 55-69 years. Participants were divided into two groups: one received both the topical formula and oral melatonin supplementation (Group A), while the other received a topical melatonin-based formula (Group B).
View Article and Find Full Text PDFJ Cosmet Dermatol
January 2025
Human Dermatology Clinic, Incheon, Republic of Korea.
Background: Intradermal injection of CPM-HA20G, a low-viscoelasticity hyaluronic acid (HA) dermal filler with glycerol, has been shown to be effective for facial rejuvenation in Caucasians, but research in Asians is limited.
Aims: This study aimed to evaluate the effectiveness and safety of CPM-HA20G in enhancing facial skin quality in Korean women using a protocol developed by local aesthetic experts.
Patients/methods: In this 24-week prospective, single-arm, open-label study, 20 women received CPM-HA20G injections in the immediate subdermal layer on the anterior cheek (1 mL per side; total 2 mL) in three sessions every 4 weeks.
Int J Pharm
January 2025
University of Turin, Department of Drug Science and Technology, via Pietro Giuria 9, 10125 Turin, Italy; University of Turin, Department of Medical Sciences, Dermatologic Clinic, Via Cherasco 23, 10126 Turin, Italy.
The constant exposure of the skin to internal and external stimuli drives towards skin aging and lost in skin hydration and elasticity. Chronic low-grade inflammation, called inflammaging, and oxidative stress are the leading causes of this phenomenon. Fatty acid coacervation is a preparation method for Solid Lipid Nanoparticles (SLNs), which does not employ solvents, and is associated to low energy consumption.
View Article and Find Full Text PDFJ Cosmet Dermatol
January 2025
Department of Dermatology, University of Athens School of Medicine, Andreas Sygros Hospital, Athens, Greece.
Objective: NCTF135HA, a versatile polyrevitalizing solution, is a potent agent for enhancing skin quality, radiance, moisture, vitality, and diminishing fine wrinkles caused by aging factors. Data demonstrate a divergence in its application from skin quality enhancement to treatment of vitiligo lesions. To know more precisely about the protocol of use among providers, alone or in combination with other procedures, we performed an international survey.
View Article and Find Full Text PDFJ Cutan Med Surg
January 2025
Windsor Clinical Research, Windsor, ON, Canada.
Acne vulgaris (AV) is a common skin condition that can cause substantial psychosocial impact. Treatments of AV target clearing and prevention of lesions and reducing scarring and dyspigmentation. Numerous medications are used to target one or more of the pathogenetic factors contributing to AV.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!