Background: Residual neuromuscular blockade (RNMB) is a frequent event after general anesthesia, which can lead to serious complications, such as upper airway obstruction. Sugammadex is useful in reversing RNMB. However, its use in infants has not yet been approved by the Food and Drug Administration. Therefore, anesthesiologists can be hesitant use it, even in situations where no other choice is available.
Case: A two-month-old baby presented to the hospital for umbilical polypectomy. At the end of the surgery, neostigmine was administered. Even after waiting for 30 min and injecting an additional dose of neostigmine, neuromuscular blockade was not adequately reversed. Eventually, sugammadex was administered, and spontaneous breathing returned.
Conclusions: If there were no particular causes of delayed return to spontaneous breathing in infants, RNMB should be considered and reversal with sugammadex would be useful.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841263 | PMC |
| http://dx.doi.org/10.17085/apm.21071 | DOI Listing |
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Article Synopsis
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- Liver damage, which can stem from various causes including drug toxicity and metabolic disorders, impairs drug metabolism and can lead to systemic complications, ultimately impacting the use of muscle relaxants in patients with liver disease.
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