Aggregation induced emission materials for tissue imaging.

Prog Mol Biol Transl Sci

Polymers and Functional Materials Division, CSIR-Indian Institute of Chemical Technology, Hyderabad, Telangana, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, India. Electronic address:

Published: January 2022

Aggregation Induced Emission (AIE) has ample opportunities in the sensing and biomedical field. Recently, AIE molecular architecture, AIE nanoparticles (NPs) and AIE conjugated polymer (CP) probes have shown outstanding performance in bioimaging applications. In this chapter, we are summarizing the updated advancement in AIE based molecular, NP and CP probes for tissue imaging. We are focusing in vivo and in vitro tissue imaging with in-depth morphological and molecular information using microscopic techniques. Also, we have summarized various infrared windows for fluorescence microscopic technique to achieve deep penetration and high resolution of tissue images. In addition, future difficulties and challenges of AIEgens in tissue imaging are shortly discussed.

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http://dx.doi.org/10.1016/bs.pmbts.2021.07.005DOI Listing

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