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Background: Radiotherapy (RT) has numerous effects on the oral mucosa, primarily genetic alterations and changes in the microenvironment. The characteristics of oral leukoplakia (OL) may differ between patients who have received previous head and neck cancer (HNC) treatment with radiation therapy and those who have not. Due to a lack of data on this scenario, we aimed to investigate the surgical outcomes of OL by comparing these two patient groups.

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Objective: To investigate blood pressure rhythm (BPR) in deficiency syndrome of hypertension (YDSH) patients and develop a random forest model for predicting YDSH.

Methods: Our study was consistent with technical processes and specification for developing guidelines of Evidence-based Chinese medicine clinical practice (T/CACM 1032-2017). We enrolled 234 patients who had been diagnosed with primary hypertension without antihypertensive medications prior to the enrollment.

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Transcriptional effects of carbon and nitrogen starvation on Ganoderma boninense, an oil palm phytopathogen.

Mol Biol Rep

January 2024

Malaysian Palm Oil Board, 6, Persiaran Institusi, Bandar Baru Bangi, 43000, Kajang, Selangor, Malaysia.

Background: Ganoderma boninense is a phytopathogen of oil palm, causing basal and upper stem rot diseases.

Methods: The genome sequence was used as a reference to study gene expression during growth in a starved carbon (C) and nitrogen (N) environment with minimal sugar and sawdust as initial energy sources. This study was conducted to mimic possible limitations of the C-N nutrient sources during the growth of G.

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Oral submucous fibrosis (OSF) is a chronic, progressive and potentially malignant oral mucosal disease. Patients often have a habit of chewing betel nuts. Areca catechu has been listed as a Class 1 carcinogen by the International Agency for Research on Cancer (IARC), and its main active component, arecoline, is classified as a Group 2B carcinogen by the IARC.

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Article Synopsis
  • Basal stem rot caused by Ganoderma boninense is a significant threat to oil palm crops in major producing countries.
  • Researchers tested various non-pathogenic polypore fungi for their potential to control this pathogen, evaluating 21 different isolates.
  • Three isolates (SRP11, SRP17, and SRP18) demonstrated strong antagonistic effects on G. boninense, with notable growth inhibition, and were identified as Fomes sp., Trametes elegans, and Trametes lactinea, respectively.
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