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A novel technique for heart-thymus en bloc transplantation in nonhuman primates.
Sci Rep
December 2024
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, USA.
The thymus is a rich source of regulatory T cells and plays a role in self-tolerance. Therefore, transplantation of a vascularized donor thymus may facilitate the induction of tolerance in recipients of a cotransplanted heart allograft. To investigate this hypothesis, we developed a new technique to procure the heart and thymus en bloc from juvenile donors and transplant the composite allograft into thymectomized recipients.
View Article and Find Full Text PDFBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.
Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer.
60 Years After the First Woman Cardiac Surgeon: We Still Need More Women in Cardiac Surgery.
CJC Open
December 2021
Department of Medicine, Division of Cardiology, McMaster University, Hamilton, Ontario, Canada.
In 1960, Dr Nina Starr Braunwald became the first woman to perform open heart surgery. Sixty years later, despite the fact that women outnumbered men in American medical school in 2017, men still dominate the field of cardiac surgery. Women surgeons remain underrepresented in cardiac surgery; 11% of practicing cardiac surgeons in Canada were women in 2015, and 6% of practicing adult cardiac surgeons in the US were women in 2019.
View Article and Find Full Text PDFNina Starr Braunwald: A Woman Pioneer in Cardiothoracic Surgery.
Ann Thorac Surg
September 2022
Department of Surgery, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, NY 11554.
"Gutta Cavat Lapidem": The legacy of Dr. Nina Starr Braunwald.
J Card Surg
October 2021
International School of Cardiac Surgery, Ettore Majorana Foundation and Center for Scientific Culture, Erice, Italy.
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