Phytochemical profiling was undertaken on the crude extracts of the bulbs, stems, and the fruits of , to determine the nature of the chemical constituents present. This represents the first study to investigate the fruits of a species of . In total, 13 new and 17 previously reported compounds were isolated and identified. The new compounds were of the phenylphenalenone-type class, with a representative of a novel structural form, named tentatively "oxabenzochromenone" (), a compound akin to an intermediate in a recently proposed phenylphenalenone metabolic network (), seven new phenylphenalenones (-), four new phenylbenzoisochromenones (-), and a new phenylbenzoisochromenone derivative (). The previously reported compounds identified were of the following structure classes: oxabenzochrysenone (, -), flavonol (, ), phenylbenzoisochromenone (, , , -), and phenylphenalenone (, ). Compounds -, -, -, , , and were subjected to antimicrobial evaluation with moderate activity observed against MRSA and slight activity against and . Compounds , -, , and were also evaluated for anthelminthic activity against larvae of the blood-feeding parasitic nematode .
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http://dx.doi.org/10.1021/acs.jnatprod.1c00509 | DOI Listing |
Biomed Res Int
December 2024
Department of Biochemistry & Chemistry, Sylhet Agricultural University, Sylhet, Bangladesh.
Emerging multidrug-resistant (MDR) strains are the main challenges to the progression of new drug discovery. To diminish infectious disease-causing pathogens, new antibiotics are required while the drying pipeline of potent antibiotics is adding to the severity. Plant secondary metabolites or phytochemicals including alkaloids, phenols, flavonoids, and terpenes have successfully demonstrated their inhibitory potential against the drug-resistant pathogens.
View Article and Find Full Text PDFSci Rep
December 2024
Agri-food Technology and Quality Laboratory, Regional Centre of Agricultural Research of Tadla, National Institute of Agricultural research (INRA), Avenue Ennasr, BP 415 Rabat principal, Rabat, 10090, Morocco.
The phytochemical, nutritional, and biological features of wild carob pulp from Tanzight (TN), Ait-Waada (AW), and Tizi-ghnayn (TG) in Azilal were studied. The results of the study reveal that the carob pulp examined has a low-fat level. AW had the most total sugar (78.
View Article and Find Full Text PDFJ Food Sci
December 2024
Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco (CIATEJ) Unidad Sureste, Tablaje Catastral Km 5.5 Carretera Sierra Papacal-Chuburná Puerto, Parque Científico Tecnológico de, Yucatán, Mexico.
The effect of solvents with different polarities on the recovery of phytochemicals (carotenoids, capsaicinoids, and phenolic compounds) from habanero pepper (Capsicum chinense) and their association with antioxidant activity (ABTS and DPPH) was evaluated through Ultra-Performance-Liquid Chromatography coupled with a Photodiode Array Detector and a Electrospray Ionization Mass Spectrometry (UPLC-PDA-ESI-MS)-based chemometric analysis, including linear correlation, multiple linear regression, and principal component analysis (PCA). The solvent polarity scale was established according to solvent dielectric constants (ɛ). Color variation (ΔE) was used to determine the presence of carotenoids, with the highest ΔE obtained using low-polarity solvents (hexane and ethyl acetate).
View Article and Find Full Text PDF<b>Background and Objective:</b> Turmeric, strawberries and broccoli are popular in the community for their beneficial effects in improving lipid profile, but poor bioavailability and absorption of their phytochemical compounds might reduce their effects while given separately. Therefore, their combination might provide a synergistic enhancement of their property as hypolipidemic agents. This study aims to examine the effects of turmeric, strawberry and broccoli in improving lipid profile in adult patients with hypercholesterolemia.
View Article and Find Full Text PDFMetabolites
December 2024
Developmental Biology Department, Institute of Biology Bucharest of Romanian Academy, 296 Splaiul Independentei, 060031 Bucharest, Romania.
This research article delves into Babaco fruit's-an Ecuadorian product with immense nutraceutical potential phytochemical composition and biological activity-in different maturation fruit stages. Bridging the gap between food and medicine, nutraceuticals offer health benefits beyond basic nutrition. Specifically, this study investigates Babaco's antioxidant and its phenolic and flavonoid content across different ripening stages: physiological maturity, organoleptic quality immaturity, and commercial maturity.
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