SARS-CoV-2 variants as super cell fusers: cause or consequence of COVID-19 severity?

EMBO J

Center for Integrative Infectious Diseases Research (CIID), Virology, University Hospital Heidelberg, Heidelberg, Germany.

Published: December 2021

The most severe forms of coronavirus disease 2019 (COVID-19) are often associated with the presence of syncytia in the lungs resulting from cell-cell fusion mediated by the SARS-CoV-2 spike protein. In this issue, Rajah and colleagues show that the SARS-CoV-2 alpha, beta, and delta variants promote enhanced syncytia formation as compared to the original strain.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8646788PMC
http://dx.doi.org/10.15252/embj.2021110041DOI Listing

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