The demand for novel and improved medicine from biological sources to cater to the biopharmaceutical sector has increased significantly in recent years. Among the vast and miscellaneous microbial diversity, fungi provide a prolific source of structurally unique and biologically active secondary metabolites. Natural products obtained from fungi have reformed the era of biomedicine, providing effective drugs that have diverse healing potential. In this review, we focus on the isolation, chemical structure, and bioactivity of biomolecules that have been identified and studied for the first time. Further, we also explain in substantial detail that how the vast uninvestigated Emericellopsis and Simplicillium species may serve as a potential treasure trove of chemically diverse compounds.
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http://dx.doi.org/10.1002/bab.2281 | DOI Listing |
Stud Mycol
December 2024
Department of Plant Pathology and Microbiology, College of Bioresources and Agriculture, National Taiwan University, Taipei, Taiwan.
Species classified in () include multiple entomopathogenic fungi. Numerous changes have recently occurred in the nomenclature of cordycipitaceous fungi due to the single naming system proposed for pleomorphic fungi in 2011. Species of are widely applied as herbal medicines, especially in Asian cultures.
View Article and Find Full Text PDFBiotechnol Appl Biochem
October 2022
Department of Chemical Engineering, Parul Institute of Technology, Parul University, Vadodara, Gujarat.
The demand for novel and improved medicine from biological sources to cater to the biopharmaceutical sector has increased significantly in recent years. Among the vast and miscellaneous microbial diversity, fungi provide a prolific source of structurally unique and biologically active secondary metabolites. Natural products obtained from fungi have reformed the era of biomedicine, providing effective drugs that have diverse healing potential.
View Article and Find Full Text PDFGenet Mol Biol
October 2021
Universidade Federal do Rio Grande do Sul, Centro de Biotecnologia, Programa de Pós-graduação em Biologia Celular e Molecular, Porto Alegre, RS, Brazil.
Filamentous fungi are the organisms of choice for most industrial biotechnology. Some species can produce a variety of secondary metabolites and enzymes of commercial interest, and the production of valuable molecules has been enhanced through different molecular tools. Methods for genetic manipulation and transformation have been essential for the optimization of these organisms.
View Article and Find Full Text PDFSci Rep
July 2021
Department of Ecology, Institute of Fungus Resources, College of Life Sciences, Guizhou University, Guiyang, 550025, Guizhou, People's Republic of China.
Simplicillium species are commonly found from soil, seawater, rock surface, decayed wood, air and as symbiotic, endophytic, entomopathogenic and mycoparasitic fungi. Minority insect-associated species was reported. Simplicillium coccinellidae, S.
View Article and Find Full Text PDFHousehold air conditioners are known to be contaminated with dematiaceous fungi such as genus Toxicocladosporium and genus Cladosporium. We frequently encounter cases in which a large amount of fungi, which are presumed to belong to the family Cordycipitaceae, are isolated from the blowout air of the household air conditioners. Therefore, the Cordycipitaceae isolated in the survey of four cases of the air conditioners were identified by genetic analyses.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!