The genus Simplicillium and Emericellopsis: A review of phytochemistry and pharmacology.

Biotechnol Appl Biochem

Department of Chemical Engineering, Parul Institute of Technology, Parul University, Vadodara, Gujarat.

Published: October 2022

AI Article Synopsis

  • The biopharmaceutical sector is increasingly seeking new and improved medicines derived from biological sources, particularly fungi, due to their unique and potent secondary metabolites.
  • Fungal natural products have transformed biomedicine by yielding effective drugs with a wide range of healing properties.
  • This review emphasizes the exploration of previously unstudied fungi species, Emericellopsis and Simplicillium, as potential sources of diverse and valuable chemical compounds.

Article Abstract

The demand for novel and improved medicine from biological sources to cater to the biopharmaceutical sector has increased significantly in recent years. Among the vast and miscellaneous microbial diversity, fungi provide a prolific source of structurally unique and biologically active secondary metabolites. Natural products obtained from fungi have reformed the era of biomedicine, providing effective drugs that have diverse healing potential. In this review, we focus on the isolation, chemical structure, and bioactivity of biomolecules that have been identified and studied for the first time. Further, we also explain in substantial detail that how the vast uninvestigated Emericellopsis and Simplicillium species may serve as a potential treasure trove of chemically diverse compounds.

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http://dx.doi.org/10.1002/bab.2281DOI Listing

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