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Clinical Characteristics of Pediatric Coats' Disease With Retinal Cyst Using Wide-Angle Fluorescein Angiography. | LitMetric
To assess the demographic and treatment features of pediatric patients of Coats' disease with retinal cyst using wide-angle FA. A retrospective, hospital based, cross-sectional study. Pediatric patients of Coats' disease underwent wide-angle FA. A retrospective review of pediatric patients of Coats' disease who underwent wide-angle FA at a single center from January 2015 to July 2020. Demographic and treatment features were compared between patients with or without retinal cyst. Demographic and treatment outcomes. There were 123 pediatric Coats' patients in our study, and 18.70% (23/123) of the patients developed complications with retinal cyst, 73.9% (17/23) of the retinal cysts were located in the inferior-temporal quadrant and 82.6% (19/23) of the retinal cysts were located in the peripheral retina anterior to the vortex veins. Compared with patients without retinal cyst, patients with retinal cyst had more clock-hours of telangiectasia on FA (7.32 vs. 5.41, = 0.031), and may need more total treatments (7.47 vs. 3.53, = 0.023) including laser photocoagulation (4.08 vs. 2.31, = 0.019) or intravitreal anti-VEGF (3.13 vs. 2.23, = 0.039), and also required a longer time for telangiectasia resolution (22.33 vs. 18.53 months, = 0.043). Pediatric patients with Coats' disease complicated by retinal cyst presented with more clock-hours of telangiectasia on FA and needed more total treatments and longer time for telangiectasia resolution.
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