Sensitization to lipid transfer protein (LTP), the most frequent cause of food allergy in southern Europe, still shows several controversial, but also intriguing, aspects. Some of these include the degree of cross-reactivity between LTPs from botanically distant sources, the definition of risk factors, the role of some cofactors, clinical outcomes, geographical differences and the identification of the primary sensitizer in different areas. This review article tries to analyse and comment on these aspects point by point suggesting some explanatory hypotheses with the final scope to stimulate critical thoughts and elicit the scientific discussion about this issue in the readership.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/cea.14049 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Downregulation of SLC7A11 by Bis(4-Hydroxy-3,5-Dimethylphenyl) Sulfone Induces Ferroptosis in Hepatocellular Carcinoma Cell.
Mol Carcinog
January 2025
Key Laboratory of Computer-Aided Drug Design of Dongguan City, The First Dongguan Affiliated Hospital, School of Pharmacy, Guangdong Medical University, Dongguan, Guangdong, China.
The progression of tumors has been demonstrated to have a strong correlation with ferroptosis. Bis(4-hydroxy-3,5-dimethylphenyl) sulfone (TMBPS) has been shown to effectively inhibit the proliferation of hepatocellular carcinoma (HCC), but its underlying mechanism is not clear. In this study, ferrostatin-1 (Fer-1) was employed to explore whether the death of HCC cells caused by TMBPS is related to ferroptosis.
View Article and Find Full Text PDFPolymers for mRNA Delivery.
Wiley Interdiscip Rev Nanomed Nanobiotechnol
January 2025
Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, China.
mRNA delivery has emerged as a transformative approach in biotechnology and medicine, offering a versatile platform for the development of novel therapeutics. Unlike traditional small molecule drugs or protein-based biologics, mRNA therapeutics have the unique ability to direct cells to generate therapeutic proteins, allowing for precise modulation of biological processes. The delivery of mRNA into target cells is a critical step in realizing the therapeutic potential of this technology.
View Article and Find Full Text PDFExosomal circ_0006896 promotes AML progression via interaction with HDAC1 and restriction of antitumor immunity.
Mol Cancer
January 2025
Department of Hematology, Qilu Hospital of Shandong University, No.117, West of Wenhua Road, Jinan, Shandong, 250012, People's Republic of China.
Background: Drug resistance and immune escape continue to contribute to poor prognosis in AML. Increasing evidence suggests that exosomes play a crucial role in AML immune microenvironment.
Methods: Sanger sequencing, RNase R and fluorescence in situ hybridization were performed to confirm the existence of circ_0006896.
Elevated Levels of Serum Alpha-2-Macroglobulin Associate with Diabetes Status and Incident Cardiovascular Disease in Type 1 Diabetes.
J Lipid Res
January 2025
Department of Medicine, University of Washington, Seattle, WA 98109.
Background: Atherosclerotic cardiovascular disease (CVD) is a major cause of death in individuals with type 1 diabetes mellitus (T1DM). However, conventional risk factors do not fully account for the increased risk. This study aimed to investigate whether serum proteins associate with diabetes status and the occurrence of CVD in T1DM.
View Article and Find Full Text PDFFrom microalgae to gastropods: Understanding the kinetics and toxicity of silver nanoparticles in freshwater aquatic environment.
Environ Pollut
January 2025
Department F.-A. Forel for Environmental and Aquatic Sciences, Section Earth and Environmental Sciences, Faculty of Sciences, University of Geneva, 66 Blvd Carl-Vogt, CH 1211 Geneva, Switzerland. Electronic address:
Silver nanoparticles (AgNPs) are increasingly used in various consumer products and industrial applications, raising concerns about their environmental impact on aquatic ecosystems. This study investigated the physicochemical stability, trophic transfer, and toxic effects of citrate-coated AgNPs in a freshwater food chain including the diatom Cyclotella meneghiniana and the gastropod Lymnaea stagnalis. AgNPs remained stable in the exposure medium, with a minimal dissolution (<0.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!