Unpacking chromatin remodelling in germ cells: implications for development and evolution.

Trends Genet

Departament de Biologia Cel.lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona (UAB), Cerdanyola del Vallès, 08193, Spain; Genome Integrity and Instability Group, Institut de Biotecnologia i Biomedicina (IBB), Universitat Autònoma de Barcelona (UAB), Cerdanyola del Vallès, 08193, Spain. Electronic address:

Published: May 2022

AI Article Synopsis

  • Germ cells hold key information about a species' evolutionary background and potential for the future.
  • Understanding the genome organization in gametocytes is crucial for grasping fertility and its effects on genetic diversity and evolution.
  • The text discusses chromatin remodeling principles in germ cell formation and how they are influenced by genome reshuffling.

Article Abstract

Germ cells reflect the evolutionary history and future potential of a species. Understanding how the genome is organised in gametocytes is fundamental to understanding fertility and its impact on genetic diversity and evolution of species. Here, we explore principles of chromatin remodelling during the formation of germ cells and how these are affected by genome reshuffling.

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Source
http://dx.doi.org/10.1016/j.tig.2021.10.007DOI Listing

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