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Direct Evidence of Excessive Charge-Carrier-Induced Degradation in InP Quantum-Dot Light-Emitting Diodes.
ACS Appl Mater Interfaces
December 2024
Department of Electronic Engineering, Kwangwoon University, Seoul 01897, Republic of Korea.
The limited operational lifetime of quantum-dot light-emitting diodes (QLEDs) poses a critical obstacle that must be addressed before their practical application. Specifically, cadmium-free InP-based QLEDs, which are environmentally benign, experience significant operational degradation due to challenges in charge-carrier confinement stemming from the composition of InP quantum dots (QDs). This study investigates the operational degradation of InP QLEDs and provides direct evidence of the degradation process.
View Article and Find Full Text PDFTransduction of Human Fetal Liver Hematopoietic CD34+ Stem and Progenitor Cells into a Cell Line by Enhancing Telomerase Activity.
Int J Hematol Oncol Stem Cell Res
October 2024
Sri Sri Institute for Advanced Research (SSIAR), Ved Vignan Maha Vidhya Peeth (VVMVP), Bangalore, India.
: Human fetal liver hematopoietic stem cells have proven potential as therapeutics but lack extensive research due to their limited supply. Even expanded fetal liver hematopoietic stem cells enter senescence or lose their self-renewal capacity after a few days in culture. The present study aimed to obtain a homogeneous and persistent supply of hematopoietic stem cells from the fetal liver by establishing a cell line through immortalization of cells by enhancing telomerase activity.
View Article and Find Full Text PDFThe double life of glucose metabolism: brain health, glycemic homeostasis, and your patients with type 2 diabetes.
BMC Med
December 2024
Sanders-Brown Center On Aging, Department of Chemistry, University of Kentucky, 249 Chemistry-Physics Building, Lexington, KY, 40506-0055, USA.
The maintenance of cognitive function is essential for quality of life and health outcomes in later years. Cognitive impairment, however, remains an undervalued long-term complication of type 2 diabetes by patients and providers alike. The burden of sustained hyperglycemia includes not only cognitive deficits but also the onset and progression of dementia-related conditions, including Alzheimer's disease (AD).
View Article and Find Full Text PDFEffect of Nanosecond Laser Texturization on Tribological Behavior of AISI 321 Stainless Steel.
Materials (Basel)
November 2024
Faculty of Mechanical Engineering, Poznań University of Technology, Piotrowo 3, 61-138 Poznań, Poland.
This study investigates how laser-induced surface modifications influence key properties such as wear resistance, hardness, and friction in dry and lubricated conditions. The research applies nanosecond pulsed laser treatment to create random, quasi-random, quasi-periodic, and periodic surface structures on the steel surface, aiming to enhance the wear resistance and reduce the coefficient of friction (COF). The frictional performance between the carbon steel ball and the texturized surface was evaluated, including an analysis of the initial friction phase contact (single, double, and multi-contact), with the surface topography assessed before and after wear.
View Article and Find Full Text PDFThe MDM2 SNP309 differentially impacts cardiorespiratory fitness in young healthy women and men.
Eur J Appl Physiol
December 2024
School of Kinesiology and Health Science, Faculty of Health, York University, 4700 Keele Street, Toronto, ON, M3J 1P3, Canada.
Purpose: Maximal oxygen consumption (VOmax), the predominant index of cardiorespiratory fitness (CRF), is a predictor of whole-body function and longevity in humans. The central cardiac function and the skeletal muscle's capacity to use oxygen are key determinants of VOmax. Murine Double Minute 2 (MDM2), mainly known as an oncogene, could regulate myocardial hypertrophy, skeletal muscle angiogenesis, and oxidative phosphorylation.
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