AI Article Synopsis
- Antimicrobial coatings can help reduce the spread of microbial diseases by being transparent, allowing for the preservation of surface visuals essential for products like cell phone screens.
- Two types of transparent coatings are discussed: one involves a polydopamine (PDA) adhesive combined with copper (PDA/Cu), while the other uses a single-step process to immobilize copper oxide (CuO) in a PDA solution (PDA/CuO).
- Both coatings effectively inactivate a high percentage of microbes, achieving more than 99% kill rates for certain bacteria and offering rapid inactivation of the SARS-CoV-2 virus within an hour.
Article Abstract
Antimicrobial coatings are one method to reduce the spread of microbial diseases. Transparent coatings preserve the visual properties of surfaces and are strictly necessary for applications such as antimicrobial cell phone screens. This work describes transparent coatings that inactivate microbes within minutes. The coatings are based on a polydopamine (PDA) adhesive, which has the useful property that the monomer can be sprayed, and then the monomer polymerizes in a conformal film at room temperature. Two coatings are described (1) a coating where PDA is deposited first and then a thin layer of copper is grown on the PDA by electroless deposition (PDA/Cu) and (2) a coating where a suspension of CuO particles in a PDA solution is deposited in a single step (PDA/CuO). In the second coating, PDA menisci bind CuO particles to the solid surface. Both coatings are transparent and are highly efficient in inactivating microbes. PDA/Cu kills >99.99% of and 99.18% of methicillin-resistant (MRSA) in only 10 min and inactivates 99.98% of SARS-CoV-2 virus in 1 h. PDA/CuO kills 99.94% of and 96.82% of MRSA within 10 min and inactivates 99.88% of SARS-CoV-2 in 1 h.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609913 | PMC |
| http://dx.doi.org/10.1021/acsami.1c15505 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
In Situ Focused Ion Beam Redeposition Surface Coatings for Site-Specific, Near-Surface Characterization by Atom Probe Tomography.
Microsc Microanal
January 2025
Department of Materials Science and Engineering, McMaster University, Hamilton, Ontario L8S 4L7, Canada.
Atom probe tomography (APT) enables three-dimensional chemical mapping with near-atomic scale resolution. However, this method requires precise sample preparation, which is typically achieved using a focused ion beam (FIB) microscope. As the ion beam induces some degree of damage to the sample, it is necessary to apply a protective layer over the region of interest (ROI).
View Article and Find Full Text PDFSurface State Control of Apatite Nanoparticles by pH Adjusters for Highly Biocompatible Coatings.
ACS Appl Mater Interfaces
January 2025
Department of Materials Science and Technology, Nagaoka University of Technology, 1603-1 Kamitomioka, Nagaoka, Niigata 940-2188, Japan.
Apatite nanoparticles are biocompatible nanomaterials, so their film formation on biodevices is expected to provide effective bonding with living organisms. However, the biodevice-apatite interfaces have not yet been elucidated because there is little experimental evaluation and discussion on the nanoscale interactions, as well as the apatite surface reactivities. Our group has demonstrated the biomolecular adsorption properties on a quartz crystal microbalance with dissipation (QCM-D) sensor coated with apatite nanoparticles, demonstrating the applicability of apatite nanoparticle films on devices.
View Article and Find Full Text PDFCharacterization of Thin Polymer Layer Prepared from Liposomes and Polyelectrolytes for TGF-β Release in Tissue Engineering.
Macromol Biosci
January 2025
Institute for Technical Chemistry, Macromolecular Chemistry, TU Braunschweig, Hagenring 30, 38106, Braunschweig, Germany.
Implant-integrated drug delivery systems that enable the release of biologically active factors can be part of an in situ tissue engineering approach to restore biological function. Implants can be functionalized with drug-loaded nanoparticles through a layer-by-layer assembly. Such coatings can release biologically active levels of growth factors.
View Article and Find Full Text PDFEnhancing Hemocompatibility in ECMO Systems With a Fibrinolytic Interactive Coating: in Vitro Evaluation of Blood Clot Lysis Using a 3D Microfluidic Model.
Macromol Biosci
January 2025
Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Carrer de Baldiri Reixac, 10, 12, Barcelona, 08028, Spain.
Blood-contacting medical devices, especially extracorporeal membrane oxygenators (ECMOs), are highly susceptible to surface-induced coagulation because of their extensive surface area. This can compromise device functionality and lead to life-threatening complications. High doses of anticoagulants, combined with anti-thrombogenic surface coatings, are typically employed to mitigate this risk, but such treatment can lead to hemorrhagic complications.
View Article and Find Full Text PDFLFP via Nanoscale Surface Reforming with a Tiny Minimal Amount of Conductivity-Enhancing Material.
Langmuir
January 2025
Department of Mechanical Engineering, Gachon University, 1342 Seongnamdaero, Sujeong-gu, Seongnam-si, Gyeonggi-do 13120, Republic of Korea.
LiFePO (LFP) typically requires a conductive additive to improve its low ion and electron conductivity. In this study, we achieved significant enhancements in Li and electron mobility by applying a minimal amount of conductive material through a new coating process. The coin cell demonstrated an excellent capacity of 157.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!