Social data has shown important role in tracking, monitoring and risk management of disasters. Indeed, several works focused on the benefits of social data analysis for the healthcare practices and curing domain. Similarly, these data are exploited now for tracking the COVID-19 pandemic but the majority of works exploited Twitter as source. In this paper, we choose to exploit Facebook, rarely used, for tracking the evolution of COVID-19 related trends. In fact, a multilingual dataset covering 7 languages (English (EN), Arabic (AR), Spanish (ES), Italian (IT), German (DE), French (FR) and Japanese (JP)) is extracted from Facebook public posts. The proposal is an analytics process including a data gathering step, pre-processing, LDA-based topic modeling and presentation module using graph structure. Data analysing covers the duration spanned from January 1st, 2020 to May 15, 2020 divided on three periods in cumulative way: first period January-February, second period March-April and the last one to 15 May. The results showed that the extracted topics correspond to the chronological development of what has been circulated around the pandemic and the measures that have been taken according to the various languages under discussion representing several countries.
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http://dx.doi.org/10.1007/s10489-020-02033-3 | DOI Listing |
ACS Nano
January 2025
School of Medicine, Nankai University, Tianjin 300071, China.
Designing dual-targeted nanomedicines to enhance tumor delivery efficacy is a complex challenge, largely due to the barrier posed by blood vessels during systemic delivery. Effective transport across endothelial cells is, therefore, a critical topic of study. Herein, we present a synthetic biology-based approach to engineer dual-targeted ferritin nanocages (Dt-FTn) for understanding receptor-mediated transport across tumor endothelial cells.
View Article and Find Full Text PDFBiochem Mol Biol Educ
January 2025
Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, USA.
We created a novel laboratory experience where undergraduate students explore the techniques used to study protein misfolding, unfolding, and aggregation. Despite the importance of protein misfolding and aggregation diseases, protein unfolding is not typically explored in undergraduate biochemistry laboratory classes. Yeast alcohol dehydrogenase (YADH) is used in the undergraduate biochemistry laboratory course at Miami University as the model system to explore protein overexpression and purification, bioinformatics, and enzyme characterization.
View Article and Find Full Text PDFBMJ Evid Based Med
December 2024
RTI International, Research Triangle Park, North Carolina, USA.
BMJ
December 2024
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02120, USA.
Objective: To compare the effectiveness and safety of budesonide-glycopyrrolate-formoterol, a twice daily metered dose inhaler, and fluticasone-umeclidinium-vilanterol, a once daily dry powder inhaler, in patients with chronic obstructive pulmonary disease (COPD) treated in routine clinical practice.
Design: New user cohort study.
Setting: Longitudinal commercial US claims data.
J Clin Med
January 2025
Anesthesiology, Critical Care and Pain Medicine Division, Department of Medicine and Surgery, University of Parma, Viale Gramsci 14, 43126 Parma, Italy.
Sepsis is one of the leading causes of mortality in hospital settings, and early diagnosis is a crucial challenge to improve clinical outcomes. Artificial intelligence (AI) is emerging as a valuable resource to address this challenge, with numerous investigations exploring its application to predict and diagnose sepsis early, as well as personalizing its treatment. Machine learning (ML) models are able to use clinical data collected from hospital Electronic Health Records or continuous monitoring to predict patients at risk of sepsis hours before the onset of symptoms.
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