Alterations to the extracellular matrix have long been associated with cancer progression and therapeutic resistance. Schwörer et al. describe a mechanism whereby fibroblasts reroute metabolites to fuel the demands of collagen synthesis, leading to cancer progression.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383054PMC
http://dx.doi.org/10.1038/s42255-021-00473-wDOI Listing

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