We report a rapid increase in enterovirus D68 (EV-D68) infections, with 139 cases reported from eight European countries between 31 July and 14 October 2021. This upsurge is in line with the seasonality of EV-D68 and was presumably stimulated by the widespread reopening after COVID-19 lockdown. Most cases were identified in September, but more are to be expected in the coming months. Reinforcement of clinical awareness, diagnostic capacities and surveillance of EV-D68 is urgently needed in Europe.
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http://dx.doi.org/10.2807/1560-7917.ES.2021.26.45.2100998 | DOI Listing |
Tanaffos
January 2024
Virology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: Rhinoviruses are known as the leading pathogens of respiratory diseases. Determining the prevalence and phylogeny of rhinoviruses plays a pivotal role in producing vaccines and medications and preventing virus complications. This study investigated the frequency, and genetic variation of rhinoviruses detected in patients referred to Masih Daneshvari Hospital.
View Article and Find Full Text PDFInfluenza Other Respir Viruses
December 2024
Infection and Immunity Research Strength, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.
Enterovirus-D68 (EV-D68) was first identified in 1962 in pediatric patients with acute respiratory conditions in California, USA (US). From the 1970s to 2005, EV-D68 was underestimated due to limited data and serotyping methods. In 2014, the United States experienced outbreaks of acute flaccid myelitis (AFM) in children EV-D68 positive.
View Article and Find Full Text PDFJ Microbiol Biotechnol
November 2024
Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan 16150, Malaysia.
Andrographolide, a bioactive compound from Andrographis paniculata, has gained attention for its antimicrobial properties, which include antibacterial, antiviral, antifungal, and antiprotozoal effects. As an herbal extract used in traditional medicines, andrographolide also shows promise for developing new antimicrobial agents, especially in the fight against rising antimicrobial resistance. Following the PRISMA 2020 guidelines, 16 peer-reviewed studies published from 2010 to 2024 and focusing on andrographolide's effects on bacteria, viruses, fungi, and protozoa were reviewed.
View Article and Find Full Text PDFbioRxiv
December 2024
Department of Microbiology and Immunology and Center for Pathogen Research, University of Maryland School of Medicine, 685 W. Baltimore Avenue, Baltimore, MD 21201, USA.
Enterovirus-D68 (EV-D68) is a plus-strand RNA virus that primarily causes infant respiratory infections. In rare pediatric cases, infection with EV-D68 has been associated with acute flaccid myelitis, a polio-like paralytic disease. We have previously demonstrated that EV-D68 induces nonselective autophagy for its benefit.
View Article and Find Full Text PDFPLoS One
December 2024
Department of Virology II, National Institute of Infectious Diseases, Musashi-murayama, Tokyo, Japan.
Enteroviruses and rhinoviruses are highly diverse, with over 300 identified types. Reverse transcription-polymerase chain reaction (RT-PCR) assays targeting their VP1, VP4, and partial VP2 (VP4-pVP2) genomic regions are used for detection and identification. The VP4-pVP2 region is particularly sensitive to RT-PCR detection, making it efficient for clinical specimen analysis.
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