AI Article Synopsis
- Thiamine is essential for energy metabolism and is crucial for various enzymatic processes in the body.
- Patients on total parenteral nutrition may develop thiamine deficiency due to factors like renal loss or increased bodily needs.
- An infant who received a liver transplant showed significant improvement in progressive lactic acidosis after receiving thiamine, highlighting its importance in patients lacking this vitamin during total parenteral nutrition.
Article Abstract
Thiamine is the cofactor of many enzymes involved in energy metabolism. Patients under total parenteral nutrition are at risk for thiamine deficiency if there is renal thiamine loss or increased thiamine requirements to mitigate systemic diseases. Thiamine deficiency symptoms include seizures, neuropathy, ataxia, peripheral vasodilation, myocardial insufficiency, sudden collapse, and death. In this report, we present an infant liver transplant recipient with progressive lactic acidosis that responded well to thiamine replacement to mitigate a lack of thiamine in total parenteral nutrition.
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| http://dx.doi.org/10.6002/ect.2021.0249 | DOI Listing |
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