AI Article Synopsis

  • - The study explored how muscle activation and motor unit number estimation (MUNE) affect the rate of torque development (RTD) during rapid muscle contractions in younger (average age 22) and older men (average age 74).
  • - Researchers recorded early phase RTD and muscle excitation using surface electromyography from the quadriceps, finding that muscle activation significantly influenced RTD, especially in older men.
  • - The results indicated that older adults rely more on muscle activation at the start of contractions than younger adults, while MUNE did not significantly impact RTD for either age group.

Article Abstract

This study examined the influence of muscle activation and motor unit number estimation (MUNE) on early phase voluntary rate of torque development (RTD) in younger (YM) and older (OM) men. Thirty-two YM (n = 17; Age = 22 yrs) and OM (n = 15; Age = 74 yrs) volunteered to participate in this study. Early phase RTD (first 50 ms of a rapid isometric contraction; RTD) and normalized surface electromyography (first 50 ms of muscle excitation; nEMG) were recorded from the right quadricep muscle group. MUNE was examined from the right vastus lateralis. Multiple linear regression analyses revealed that nEMG had a significant effect on RTD independent of age group ( ≤ 0.001). nEMG had a significant effect on RTD in the OM group (p = 0.037). MUNE had no effect on RTD independent of age. Older adults may depend more on muscle activation at contraction onset of early phase RTD compared to younger adults.

Download full-text PDF

Source
http://dx.doi.org/10.1080/00222895.2021.2001412DOI Listing

Publication Analysis

Top Keywords

early phase
16
muscle activation
12
motor unit
8
unit number
8
rate torque
8
torque development
8
younger older
8
older men
8
age yrs
8
phase rtd
8

Similar Publications

Introduction: Rheumatoid arthritis (RA) is a progressive autoimmune inflammatory disease. According to the European League Against Rheumatism (EULAR), the stages of RA progression include pre-RA, preclinical RA, inflammatory arthralgia, arthralgia with positive antibodies, arthralgia suspected of progressing to RA, undifferentiated arthritis and finally established RA. According to the Community Oriented Program for Control of Rheumatic Diseases (COPCORD), the prevalence of RA in Mexico is 1.

View Article and Find Full Text PDF

With the advancement of precise hepatobiliary surgery concepts, the diagnostic and therapeutic approaches for hepatic echinococcosis have undergone significant transformations. However, whether these changes have correspondingly improved patient outcomes remains unclear. A retrospective analysis of these changes will provide crucial guidance for the prevention and treatment of hepatic echinococcosis.

View Article and Find Full Text PDF

Development and Validation of a Nomogram Based on Multiparametric MRI for Predicting Lymph Node Metastasis in Endometrial Cancer: A Retrospective Cohort Study.

Acad Radiol

December 2024

Department of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China (Y.T., Y.W., Y.Y., X.Q., Y.H., J.L.); Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor (Guangxi Medical University), Ministry of Education, Nanning 530021, Guangxi Zhuang Autonomous Region, PR China (J.L.). Electronic address:

Rationale And Objectives: To develop a radiomics nomogram based on clinical and magnetic resonance features to predict lymph node metastasis (LNM) in endometrial cancer (EC).

Materials And Methods: We retrospectively collected 308 patients with endometrial cancer (EC) from two centers. These patients were divided into a training set (n=155), a test set (n=67), and an external validation set (n=86).

View Article and Find Full Text PDF

The phosphodiesterase-4 inhibitor Zl-n-91 suppresses glioblastoma growth via EGR1/PTEN/AKT pathway.

Eur J Pharmacol

December 2024

The School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, PR China. Electronic address:

Glioblastoma multiforme (GBM) is a highly heterogeneous and aggressive brain tumor, which presents significant challenges for treatment in clinical settings. Phosphodiesterase 4 (PDE4) inhibitors can prevent the degradation of cAMP and have been used as a potential targeted therapeutic approach for different cancer types. However, its clinical use is restricted by the side effects such as nausea and vomiting.

View Article and Find Full Text PDF

Electrophysiological Insights into Alzheimer's Disease: A Review of Human and Animal Studies.

Neurosci Biobehav Rev

December 2024

Interdisciplinary Neuroscience Program, University of Nevada, Las Vegas; Department of Psychology, University of Nevada, Las Vegas.

This review highlights the crucial role of neuroelectrophysiology in illuminating the mechanisms underlying Alzheimer's disease (AD) pathogenesis and progression, emphasizing its potential to inform the development of effective treatments. Electrophysiological techniques provide unparalleled precision in exploring the intricate networks affected by AD, offering insights into the synaptic dysfunction, network alterations, and oscillatory abnormalities that characterize the disease. We discuss a range of electrophysiological methods, from non-invasive clinical techniques like electroencephalography and magnetoencephalography to invasive recordings in animal models.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!