An asymmetric transfer hydrogenation (ATH) of quinolines in water or biphasic systems was developed. This ATH reaction proceeds smoothly without the need for inert atmosphere protection in the presence of a water-soluble iridium catalyst, which bears an easily available aminobenzimidazole ligand. This ATH system can work at a catalyst loading of 0.001 mol % (S/C = 100 000, turnover number (TON) of up to 33 000) under mild reaction conditions. The turnover frequency (TOF) value can reach as high as 90 000 h. A variety of quinoline and -heteroaryl compounds are transformed into the desired products in high yield and up to 99% enantiomeric excess (ee).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.joc.1c01925 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Stabilizing the Fe Species of Nickel-Iron Double Hydroxide via Chelating Asymmetric Aldehyde-Containing THB Ligand for Long-Lasting Water Oxidation.
Adv Mater
December 2024
State Key Lab of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China.
Nickel-iron layered double hydroxides (NiFe LDHs) are considered as promising substitutes for precious metals in oxygen evolution reaction (OER). However, most of the reported NiFe LDHs suffer from poor long-term stability because of the Fe loss during OER resulting in severe inactivation. Herein, a dynamically stable chelating interface through in situ transformation of asymmetric aldehyde-ligand (THB, 1,3,5-Tris(3'-hydroxy-4'-formylphenyl)-benzene) modified NiFe LDHs to anchor Fe and significantly enhance the OER stability is reported.
View Article and Find Full Text PDFPt single atoms promoting the construction of asymmetric double sites to achieve highly selective photoreduction of CO to ethylene.
J Colloid Interface Sci
December 2024
Faculty of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500, PR China; Key Laboratory of Photochemical Conversion and Optoelectronic Materials, CAS-HKU Joint Laboratory on New Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Beijing 100049, PR China.
In this work, Pt single atoms (SAs) were engineered on the surface of CdInS (CIS) to trigger abundant generation and stable existence of sulfur vacancies (S). Through quasi in situ X-ray photoelectron spectroscopy (XPS) and work function analysis, the photogenerated electrons are first captured by Pt SAs and S, and then transferred from Pt SAs to S, ultimately increasing the electron density of S. Meanwhile, S have significant advantages in adsorbing CO molecules.
View Article and Find Full Text PDFUltrafast Thermal Switching Enabled by Transient Polaritons.
ACS Nano
December 2024
School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Ultrafast thermal switches are pivotal for managing heat generated in advanced solid-state applications, including high-speed chiplets, thermo-optical modulators, and on-chip lasers. However, conventional phonon-based switches cannot meet the demand for picosecond-level response times, and existing near-field radiative thermal switches face challenges in efficiently modulating heat transfer across vacuum gaps. To overcome these limitations, we propose an ultrafast thermal switch design based on pump-driven transient polaritons in asymmetric terminals.
View Article and Find Full Text PDFAltered Nigral Amide Proton Transfer Imaging Signal Concordant With Motor Asymmetry in Parkinson's Disease: A Multipool CEST MRI Study.
NMR Biomed
February 2025
Department of Radiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Asymmetry is a natural characteristic of Parkinson's disease (PD), which can be used to distinguish PD from atypical parkinsonism. Chemical exchange saturation transfer (CEST) has demonstrated value in reflecting the subtle changes related to neuron loss and abnormal protein accumulation in PD but has not been used to investigate asymmetry in PD. This study aimed to examine asymmetrical changes in the mesencephalic nucleus of PD patients with motor asymmetry using four-pool CEST analysis and to explore the relationship between imaging asymmetry and motor asymmetry.
View Article and Find Full Text PDFIonic liquid assisted construction of synergistic modulated multiphase hybrid composites for boosting electrochemical energy storage.
J Colloid Interface Sci
December 2024
College of Chemistry and Materials Engineering, Bohai University, Jinzhou 121013, China. Electronic address:
The unique structure and strong interaction of multiphase hybrid materials have garnered significant attention as prospective candidates for electrode materials in the realm of energy storage. The present study presents a rational design of a functional NiSe-CoSe/N, B double-doped carbon hybrid composite (NCS/C), resulting in the emergence of various novel cooperative regulatory mechanisms involving: (i) the heterogeneous structure of NiSe and CoSe generates built-in electric fields to increase electron mobility; (ii) the incorporation of polyatomic double-doped carbon (N, and B) expedites electron transfer rate; intriguingly, (iii) ionic liquids not only serve as polyatomic dopants in the reaction system but also influence the microstructure of the composite. Benefiting from these synergistic effects, the NCS/C hybrid exhibits remarkable charge storage capacity and rapid electrochemical kinetics, driven by its multi-fold hollow structure and multicomponent cooperative modulation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!