Acetone is a chemical found naturally in the environment, and acetone poisoning can occur through contact with household products that contain acetone, including nail polish removers, paint removers, some polishes, as well as certain detergents and cleaners. Acetone toxicity affects almost all body systems, including the nervous, respiratory, cardiovascular, and endocrine systems. The incidence of life-threatening medical problems from acetone exposure is very rare. However, in this report, we present a case of acetone toxicity resulting in death. Our patient presented with cardiopulmonary arrest, hypotension, tachycardia, hyperglycemia, acute kidney injury (AKI), thrombocytopenia, elevated liver enzymes, and extensive esophageal and gastric erosion with associated upper gastrointestinal bleeding.
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http://dx.doi.org/10.7759/cureus.18466 | DOI Listing |
Turk J Pharm Sci
January 2025
University of Tlemcen, Faculty of Science, Department of Chemistry, Laboratory of Natural and Bioactive Substances, Tlemcen, Algeria.
Objectives: This study focused on the phytochemical, insecticidal, and bactericidal activities of Vahl, as well as molecular docking analysis of an acetylcholinesterase (AChE) inhibitor as a promising natural insecticide.
Materials And Methods: The leaves of were successively extracted with n-hexane, acetone, and methanol. Silica gel column chromatography of the methanol extract yielded compound 1.
Sensors (Basel)
December 2024
School of Aerospace Science and Technology, Xidian University, Xi'an 710126, China.
Toxic acetone gas emissions and leakage are a potential threat to the environment and human health. Gas sensors founded on metal oxide semiconductors (MOS) have become an effective strategy for toxic gas detection with their mature process. In the present work, an efficient acetone gas sensor based on Au-modified ZnO porous nanofoam (Au/ZnO) is synthesized by polyvinylpyrrolidone-blowing followed by a calcination method.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Department of Physiology, "Iuliu Haţieganu" University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
Development of cocrystals through crystal engineering is a viable strategy to formulate poorly water-soluble active pharmaceutical ingredients as stable crystalline solid forms with enhanced bioavailability. This study presents a controlled cocrystallization process by cooling for the 1:1 cocrystal of Ketoconazole, an antifungal class II drug with the Fumaric acid coformer. This was successfully set up following the meta-stable zone width determination in acetone-water 4:6 (/) and pure ethanol.
View Article and Find Full Text PDFLife (Basel)
November 2024
Botany Department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt.
The continuous use of synthetic insecticides to suppress mosquito larvae has detrimental impacts on the environment and human health. Finding novel and target-specific bio-insecticides has become crucial. Here, the larvicidal and genotoxic activities of different extracts from and toward larvae were investigated.
View Article and Find Full Text PDFBioresour Technol
January 2025
College of Bioscience and Bioengineering, Institute of Applied Microbiology, Jiangxi Agricultural University, Nanchang, Jiangxi 330045, China. Electronic address:
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