AI Article Synopsis
- Patients with hypermobile Ehlers-Danlos Syndrome (EDS) often experience cervical dystonia, which can be complicated by treatments like botulinum toxin injections.
- In a case study, three patients received low-dose OnabotulinumtoxinA injections targeting specific myofascial areas, resulting in clinical improvement without complications.
- The patients showed a notable decrease in their dystonia symptoms on the TWSTRS scale and a measurable reduction in deep fascia thickness, supporting the treatment's safety and effectiveness.
Article Abstract
Background: Many patients with hypermobile Ehlers-Danlos Syndrome (EDS) suffer from cervical dystonia. Intramuscular injection of botulinum toxin may exacerbate myeloradiculopathy or atlantoaxial subluxation in this patient population.
Case: Three patients with hypermobile EDS underwent low-dose OnabotulinumtoxinA injections for cervical dystonia into myofascial sites selected using Fascial Manipulation diagnostic sequencing technique. All patients improved in clinical symptoms without complications.
Results: Patients clinically improved on the TWSTRS by 16 points with demonstrated changes in deep fascia thickness decrease of 0.28 mm.
Discussion: Low-dose OnabotulinumtoxinA injections into carefully selected sites is a safe and effective treatment in hypermobile EDS patients suffering from cervical dystonia.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555620 | PMC |
| http://dx.doi.org/10.5334/tohm.647 | DOI Listing |
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