We characterized strains isolated from cystic fibrosis (CF) patients during screening for multidrug-resistant strains to determine mechanisms of antibiotic resistance and conduct typing. We investigated 53 isolates collected from different CF patients, excluding multiple isolates from the same patient. Genotypic characterization was based on type (protein A); staphylococcal cassette chromosome () type for resistant to methicillin (methicillin-resistant [MRSA]); and resistance to the most common macrolides, lincosamides, and streptogramins b and fluoroquinolones. Most strains (78.41%) were resistant to one or more antibiotics; 16.96% were MRSA, whereas 69.81% showed resistance to erythromycin. MRSA strains revealed the acquisition and insertion of of class I ( = 1) (hospital-acquired), IV ( = 5), and V ( = 1) (community-acquired), along with two cases that were not typeable. We detected 34 different types, with t571 being the most frequent. The minimum spanning tree of the tested strains showed evidence of strain relatedness.
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