AI Article Synopsis
- PAHs are harmful environmental pollutants found in indoor dust, with high toxicity and significant presence in various residential areas of Ilorin City, where samples were collected over two weeks.
- The study identified fluoranthene as the most common PAH and high molecular weight PAHs made up the largest portion of these compounds, with certain carcinogenic PAHs detected in higher concentrations.
- Various sources of PAHs were determined, including indoor activities and outdoor pollution, with the research concluding that the cancer risk from these emissions in Ilorin is within acceptable limits, suggesting that monitoring and control measures could be established.
Article Abstract
Polycyclic aromatic hydrocarbons (PAHs) have attracted significant attention in recent times on account of their reasonably high environmental burden and extreme toxicity. Samples of indoor dusts were obtained daily over a period of 2 weeks from 10 residences located within low, medium, and high density residential areas of Ilorin City. The concentration levels, potential sources, and cancer health risks of sixteen polycyclic aromatic hydrocarbons (PAHs) were investigated using gas chromatography/mass spectrometry. PAHs total concentrations varied from 3.95 ± 0.19 to 8.70 ± 0.43 μg/g with arithmetic mean of 6.09 ± 0.46 μg/g. Fluoranthene was the most dominant PAHs congener. High molecular weight (HMW) PAHs (4-6 rings) were the most prevalent PAHs and were responsible for 79.29% of total PAHs in sampled residences. Chrysene (Chry) was the most abundant compound among the 7 carcinogenic PAHs (CPAHs). Moreover, diagnostic ratios and positive matrix factorization (PMF) employed to apportion PAHs suggested that indoor dusts originated from indoor activities and infiltrating outdoor air pollutants. Diagnostic ratios revealed that PAHs are from mixed sources which include coal/wood combustion, non-traffic and traffic emissions, petroleum, petrogenic (gasoline), and petroleum combustion. Similarly, positive matrix factorization (PMF) model suggested five sources (factors) were responsible for PAHs in indoor dusts comprised of petroleum combustion and traffic emissions (60.05%), wood and biomass combustion emissions (20.84%), smoke from cooking, incense burning and tobacco (4.17%), gasoline combustion from non-traffic sources (13.89%), and emissions from coal burning and electronic devices (1.05%). The incremental lifetime carcinogenic risks (ILCR) of PAHs in adults and children estimated by applying benzo(a)pyrene (BaP) equivalent were within the satisfactory risk limits in Ilorin. Indoor PAHs emissions in Ilorin residences could be monitored and controlled by using data provided in this study.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10661-021-09566-1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
sp. nov., isolated from duckweed and formal proposal to reclassify as a later heterotypic synonym of and reclassify as subsp. .
Int J Syst Evol Microbiol
January 2025
Department of Microbiology, Faculty of Science, Kasetsart University, Chatuchak, Bangkok 10900, Thailand.
A novel strain DW16-2, isolated from duckweed (), was taxonomically studied in detail. The analysis based on its 16S rRNA gene sequence revealed that the strain was most closely related to Y8 (98.8%), followed by YIM 61452 (98.
View Article and Find Full Text PDFEffects of prolonged oxytetracycline supplementation on freshwater stinging catfish (): a multi-biomarker approach.
Front Immunol
January 2025
Indian Council of Agriculture Research (ICAR)-Central Institute of Freshwater Aquaculture (CIFA), Fish Health Management Division, Bhubaneswar, Odisha, India.
Background: Aquaculture systems that sporadically depend on antibiotics can contribute to the development of adverse effects on the fish, microbial flora and the environment. This study sought to investigate the impacts of extended oxytetracycline supplementation on the freshwater stinging catfish through a multi-biomarker approach.
Methods: A total of 300 (20 ± 0.
Mitochondria-Targeting Virus-Like Gold Nanoparticles Enhance Chemophototherapeutic Efficacy Against Pancreatic Cancer in a Xenograft Mouse Model.
Int J Nanomedicine
January 2025
Key Laboratory of Nanomedical Technology (Education Department of Fujian Province), Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, People's Republic of China.
Background: The dense and fibrotic nature of the pancreatic tumor microenvironment significantly contributes to tumor invasion and metastasis. This challenging environment acts as a formidable barrier, hindering effective drug penetration and delivery, which ultimately limits the efficacy of conventional cancer treatments. Gold nanoparticles (AuNPs) have emerged as promising nanocarriers to overcome the extracellular matrix barrier; however, their limited targeting precision, poor delivery efficiency, and insufficient photothermal conversion present challenges.
View Article and Find Full Text PDFZanubrutinib plus R-CHOP for the treatment of newly diagnosed double-expressor lymphoma: A phase 2 clinical study.
Cancer
January 2025
Department of Lymphoma, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Background: Double-expressor lymphoma (DEL) has a poorer prognosis than other subtypes of diffuse large B-cell lymphoma (DLBCL). This study is a multicenter, prospective, single-arm, phase 2 clinical study initiated by investigators to evaluate the efficacy and safety of combined zanubrutinib with R-CHOP, which includes rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone for patients with DEL (stage II or more), as well as to explore factors related to efficacy preliminarily.
Methods: From November 2020 to July 2022, 48 newly diagnosed patients were enrolled.
Real-world data on utilization of neoadjuvant chemotherapy for muscle invasive bladder cancer: impact on surgical complications and oncological efficacy.
Acta Oncol
January 2025
Institute of Clinical Medicine, UIT- The Arctic University, Tromsø, Norway; Department of Urology, University Hospital of North Norway, Tromsø, Norway.
Background And Purpose: Recommended treatment of urothelial muscle-invasive bladder cancer (MIBC) is cisplatin-based neoadjuvant chemotherapy (NAC) followed by cystectomy, but there are challenges with low utilization of NAC. We aimed to evaluate the utilization of NAC, perioperative complications and oncological efficacy in a real-world setting.
Patients And Methods: All patients operated with radical cystectomy at the University Hospital of North Norway during 2011-2021 for MIBC were included.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!