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Foix Chavany Marie syndrome (FCMS), or opercular syndrome, is a rare type of pseudobulbar palsy characterized by paralysis of bilateral facio-linguovelo-masticatory and pharyngeal muscles with automatic-voluntary dissociation. This syndrome was first described by Magnus in 1837 and further defined by two French neurologists, Charles Foix and Jean Alfred Emile Chavany, along with one French pediatrician, Julie Marie, who reported it first in 1926. Since then, a few cases have been reported across the world.

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A Rare Case of a Good Neurological Outcome following Traumatic Foix-Chavany-Marie Syndrome.

Case Rep Crit Care

May 2024

Department of Intensive Care Medicine, Kantonsspital Aarau, Aarau, Switzerland.

Article Synopsis
  • Traumatic brain injury (TBI) can lead to serious long-term effects, such as disabilities and reduced quality of life, with complications like Pseudobulbar palsy and Foix-Chavany-Marie Syndrome (FCMS) being rare but significant outcomes.
  • A 58-year-old man developed FCMS after a severe cycling accident, resulting in unique symptoms like facial and throat muscle dysfunction while preserving automatic movements.
  • This case adds to the sparse knowledge on trauma-related FCMS, emphasizing the importance of early detection and comprehensive treatment for better patient recovery outcomes.
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Key Clinical Message: Unilateral opercular lesions can result in Foix-Chavany-Marie syndrome, which is marked by acute anarthria, automatic-voluntary movement dissociation-most notably the absence of voluntary facial and tongue movements-and a generally better prognosis. Better patient outcomes are mostly dependent on early detection, management, and rehabilitation.

Abstract: Opercular syndrome is a rare neurological disorder caused by bilateral or unilateral lesions of the operculum that result in symptoms related to speech and swallowing difficulties with dissociation of automatic-voluntary movements in affected muscles.

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Corticobasal syndrome mimicking Foix-Chavany-Marie syndrome with suggested 4-repeat tauopathy by tau PET.

BMC Geriatr

December 2023

Department of Functional Neurology & Neurosurgery, Center for Integrated Human Brain Science, Brain Research Institute, Niigata University, 1-757 Asahimachi-Dohri, Niigata, 951-8585, Japan.

Article Synopsis
  • Corticobasal syndrome (CBS) is a neurodegenerative disorder marked by symptoms like parkinsonism, limb apraxia, and language issues, often linked to tauopathies, while Foix-Chavany-Marie syndrome (FCMS) presents differently, featuring facial and speech difficulties, typically due to stroke or TDP-43 proteinopathy.
  • A clinical case of a 68-year-old woman initially thought to have FCMS progressively developed symptoms that led to a final diagnosis of CBS, characterized by significant speech degradation and neurological signs reflective of frontal lobe dysfunction.
  • Neuroimaging revealed 4-repeat tauopathy as the underlying pathology of CBS, and despite treatment efforts, the patient’s condition worsened rapidly, leading
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