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| http://dx.doi.org/10.1590/2175-8239-JBN-2021-E010 | DOI Listing |
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The Reality of Evaluating Urine Spot Sodium and Urine Spot Sodium Creatinine Ratio in Furosemide Stress Test as a New Biomarker in Diagnosing Progressive AKI in Critically Ill.
Indian J Crit Care Med
December 2024
Department of Anesthesiology and Critical Care, Maulana Azad Medical College (MAMC), New Delhi, India.
Chatterjee R, Gupta L. The Reality of Evaluating Urine Spot Sodium and Urine Spot Sodium Creatinine Ratio in Furosemide Stress Test as a New Biomarker in Diagnosing Progressive AKI in Critically Ill. Indian J Crit Care Med 2024;28(12):1089-1090.
View Article and Find Full Text PDFRole of Spot Urine Sodium in Furosemide Stress Test in Volume-overloaded Critically Ill Patients with Acute Kidney Injury.
Indian J Crit Care Med
December 2024
Department of Anesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Article Synopsis
- This study investigates how urine output (UO) and urine spot sodium (USS) measurements during a furosemide stress test (FST) can predict the progression of acute kidney injury (AKI) in critically ill patients.
- A total of 50 patients were assessed, with findings revealing significant differences in UO at 1 and 2 hours for those with progressive AKI compared to non-progressive cases.
- The study concludes that monitoring UO in the first two hours and the change in the urine spot sodium creatinine ratio (USSCR) within six hours post-FST could aid in distinguishing progressive AKI early on.
Bilateral Stress Fractures of Amputated Tibial Stumps in the Setting of Chronic Compartment Syndrome.
Orthop Res Rev
November 2024
Scientific Department, Scientific and Research Institute of Rehabilitation of National Pirogov Memorial Medical University, Vinnytsia, Ukraine.
Introduction: Limb amputation and subsequent prosthetics lead to significant disturbances in bone residual limb remodeling.
Aim: To familiarize specialists with the possibility of simultaneous bilateral stress fractures of amputation residual limbs resulting from intensive loads and poor-quality prosthetics causing chronic compartment syndrome. A case of bilateral stress fractures of the tibia in a 28-year-old male military serviceman with paired transtibial amputation is presented.
The therapeutic potential of Ribes orientale in hypertension: Improving electrolyte balance, enhancing antioxidant activity, and modulating the muscarinic pathway.
Ann Pharm Fr
November 2024
Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University Grossman School of Medicine, 550 1st Ave, New York, NY 10016, USA.
Cardiovascular diseases like hypertension require diuretics, but their effectiveness and side effects limit their use. Alternatives like Ribes orientale extract are being investigated for potential diuretic. In acute diuretic action, the extract and fractions of Ribes orientale were investigated in saline-loaded rats at doses of 12.
View Article and Find Full Text PDFAquaporins in sepsis- an update.
Front Immunol
November 2024
Klinik für Anästhesiologie Intensivmedizin und Schmerztherapie Universitätsklinikum Knappschaftskrankenhaus Bochum, University Clinic of Ruhr University Bochum, Bochum, Germany.
Aquaporins (AQPs), a family of membrane proteins that facilitate the transport of water and small solutes, have garnered increasing attention for their role in sepsis, not only in fluid balance but also in immune modulation and metabolic regulation. Sepsis, characterized by an excessive and dysregulated immune response to infection, leads to widespread organ dysfunction and significant mortality. This review focuses on the emerging roles of aquaporins in immune metabolism and their potential as therapeutic targets in sepsis, with particular attention to the modulation of inflammatory responses and organ protection.
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