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Cutting-edge: bionanomaterial solutions in the battle against Severe Acute Respiratory Syndrome Coronavirus 2.
Braz J Biol
January 2025
Near East University, Operational Research Center in Healthcare, Mersin, Turkey.
Amidst the ongoing COVID-19 pandemic, the imperative of our time resides in crafting stratagems of utmost precision to confront the relentless SARS-CoV-2 and quell its inexorable proliferation. A paradigm-shifting weapon in this battle lies in the realm of nanoparticles, where the amalgamation of cutting-edge nanochemistry begets a cornucopia of inventive techniques and methodologies designed to thwart the advances of this pernicious pathogen. Nanochemistry, an artful fusion of chemistry and nanoscience, provides a fertile landscape for researchers to craft innovative shields against infection.
View Article and Find Full Text PDFRevolutionizing colorectal cancer detection: A breakthrough in microbiome data analysis.
PLoS One
January 2025
Department of Computer Science, Faculty of Computing, Federal University of Lafia, Lafia, Nasarawa State, Nigeria.
Article Synopsis
- The emergence of Next Generation Sequencing (NGS) technology has transformed clinical diagnostics, providing extensive microbiome data for personalized medicine.
- Despite its potential, microbiome data's complexity and variability pose challenges for traditional statistical and machine learning approaches, including deep learning.
- The paper presents a novel feature engineering technique that combines two data feature sets, significantly improving the Deep Neural Network's performance in colorectal cancer detection, raising the Area Under the Curve (AUC) from 0.800 to 0.923, thus enhancing microbiome data analysis and disease detection capabilities.
Longitudinal Analysis of Obesity Drug Use and Public Awareness.
JAMA Netw Open
January 2025
Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Importance: Obesity, a chronic disease with escalating global prevalence, poses considerable health risks. Glucagon-like peptide 1 receptor agonists (GLP-1RAs), including liraglutide, semaglutide, and tirzepatide, have demonstrated efficacy for weight loss in clinical trials. The paradigm shift in the approach to obesity management drugs (OMDs) may offer an opportunity to examine online search activity and prescription trends.
View Article and Find Full Text PDFTransforming Medicine: Advances in Gene Therapy, Immunotherapy, and Targeted Cures.
Curr Protein Pept Sci
January 2025
Galgotias College of Pharmacy, Pharmacy, Greater Noida, Uttar Pradesh, 201310, India.
In recent years, novel therapeutic approaches have revolutionized the landscape of medicine, offering promising avenues for the cure of various diseases. The novel approaches explore advancements in gene therapy in pharmaceuticals, immunotherapy, RNA-based therapeutics, cell-based therapies, and targeted tumor therapies. Gene therapy has emerged as a groundbreaking approach, leveraging genetic material to cure or prevent diseases by targeting defective genes.
View Article and Find Full Text PDFUser-Centered Design of Neuroprosthetics: Advancements and Limitations.
CNS Neurol Disord Drug Targets
January 2025
Biosciences and Bioengineering PhD Program, American University of Sharjah, UAE.
Neurological conditions resulting from severe spinal cord injuries, brain injuries, and other traumatic incidents often lead to the loss of essential bodily functions, including sensory and motor capabilities. Traditional prosthetic devices, though standard, have limitations in delivering the required dexterity and functionality. The advent of neuroprosthetics marks a paradigm shift, aiming to bridge the gap between prosthetic devices and the human nervous system.
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