Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554459 | PMC |
| http://dx.doi.org/10.1016/j.adro.2021.100814 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Consensus guidelines for the management of pineal region tumours for low- and middle-income countries.
J Pak Med Assoc
March 2024
Department of Neurosurgery, The Aga Khan University, Karachi, Pakistan.
Article Synopsis
- * These tumors often cause obstructive hydrocephalus and symptoms such as headaches, nausea, and impaired gait due to mass effect.
- * Diagnosis primarily relies on imaging, while biopsy is required for histologic confirmation, except for germinomas, which can be identified through specific tumor markers; treatments vary from surgery for benign tumors to additional chemotherapy and radiotherapy for malignant ones.
SNO-EANO-EURACAN consensus on management of pineal parenchymal tumors.
Neuro Oncol
December 2024
Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Pineal parenchymal tumors are rare neoplasms for which evidence-based treatment recommendations are lacking. These tumors vary in biology, clinical characteristics, and prognosis, requiring treatment that ranges from surgical resection alone to intensive multimodal antineoplastic therapy. Recently, international collaborative studies have shed light on the genomic landscape of these tumors, leading to refinement in molecular-based disease classification in the 5th edition of the World Health Organization (WHO) classification of tumors of the central nervous system.
View Article and Find Full Text PDFEndoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point.
J Vis Exp
June 2024
Department of Neurosurgery, Istanbul University Faculty of Medicine.
Pineal neoplasms have a significant impact on children although they are relatively uncommon. They account for approximately 3-11% of all childhood brain tumors, which is considerably higher than the <1% seen in adult brain tumors. These tumors can be divided into three main categories: germ cell tumors, parenchymal pineal tumors, and tumors arising from related anatomical structures.
View Article and Find Full Text PDFA case of a pineal parenchymal tumor of intermediate differentiation with bifocal lesions differentiated by negative placental alkaline phosphatase in the spinal fluid.
Childs Nerv Syst
September 2024
Department of Neurosurgery, Tokyo Women's Medical University, 8-1 Kawada-cho Shinjuku-ku, Tokyo, 162-8666, Japan.
Article Synopsis
- Scientists found that checking for a special protein called PLAP in the spinal fluid helps doctors figure out if a patient has a specific type of brain tumor called a germinoma.
- They looked at a 15-year-old boy who had tumors in two places in his brain, but tests showed he didn’t have that protein, making them think it might be a different kind of tumor.
- After doing some surgery to remove the tumors, they discovered it was a less common type called a pineal parenchymal tumor, teaching doctors that PLAP can help tell different tumors apart for better treatment.
Pineal parenchymal tumors (PPTs) are rare, accounting for less than 0.3% of all primary central nervous system (CNS) tumors. Pineal parenchymal tumors of intermediate differentiation (PPTID) (WHO grade 2 or 3) show an intermediate prognosis between pineocytoma and pineoblastoma.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!