The aim of the present study is to apply the canine olfactory sensitivity to detect COVID-19-positive axillary sweat samples as a One Health approach in Latin America. One hundred volunteers with COVID-like symptoms were invited to participate, and both axillary sweat samples for dog detection and nasopharynx/oropharynx swabs for qPCR were collected. Two dogs, previously trained, detected 97.4% of the samples positive for COVID-19, including a false-negative qPCR-test, and the positive predictive value was 100% and the negative predictive value was 98.2%. Therefore, we can conclude that canine olfactory sensitivity can detect a person infected with COVID-19 through axillary sweat successfully and could be used as an alternative to screen them without invasive testing.
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http://dx.doi.org/10.3389/fpubh.2021.647903 | DOI Listing |
PLoS Negl Trop Dis
December 2024
Department of Veterinary Medicine, University of Bari, Bari, Italy.
The olfactory response of insect vectors such as phlebotomine sand flies is a key facet for investigating their interactions with vertebrate hosts and associated vector-borne pathogens. Such studies are mainly performed by assessing the electrophysiological response and the olfactory behaviour of these arthropods towards volatile organic compounds (VOCs) produced by hosts. Nonetheless, few studies are available for species of the subgenera Lutzomyia and Nyssomyia in South America, leaving a void for Old World sand fly species of the genus Phlebotomus.
View Article and Find Full Text PDFInt J Nanomedicine
December 2024
Department of Immunology, Oncology and Nanobiomedicine Initiative, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain.
Background: Severe Acute Respiratory syndrome coronavirus 2 (SARS-CoV-2) and Influenza A viruses (IAVs) are among the most important causes of viral respiratory tract infections, causing similar symptoms. IAV and SARS-CoV-2 infections can provoke mild symptoms like fever, cough, sore throat, loss of taste or smell, or they may cause more severe consequences leading to pneumonia, acute respiratory distress syndrome or even death. While treatments for IAV and SARS-CoV-2 infection are available, IAV antivirals often target viral proteins facilitating the emergence of drug-resistant viral variants.
View Article and Find Full Text PDFFront Med (Lausanne)
December 2024
Department of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Hannover, Germany.
Rapid and sensitive diagnostic measures are a pre-requisite for the control of SARS-CoV-2 outbreaks. Dogs detect SARS-CoV-2-infected human individuals with high speed due to their extraordinary olfactory acuity. In the post-pandemic phase of SARS-CoV-2 it is difficult to obtain samples from infected humans for scent dog training.
View Article and Find Full Text PDFAnimals (Basel)
November 2024
Dog Cognition Lab, Department of Psychology, Barnard College, New York, NY 10027, USA.
Spatial navigation allows animals to understand their environment position and is crucial to survival. An animal's primary mode of spatial navigation (horizontal or vertical) is dependent on how they naturally move in space. Observations of the domestic dog () have shown that they, like other terrestrial animals, navigate poorly in vertical space.
View Article and Find Full Text PDFJ Anim Sci
January 2024
Global Forensic and Justice Center and Department of Chemistry and Biochemistry, Florida International University, Miami, FL, USA 33199.
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