Accurate segmentation of optic disc (OD) and optic cup (OC) in fundus images is crucial for the analysis of many retinal diseases, such as the screening and diagnosis of glaucoma and atrophy segmentation. Due to domain shift between different datasets caused by different acquisition devices and modes and inadequate training caused by small sample dataset, the existing deep-learning-based OD and OC segmentation networks have poor generalization ability for different fundus image datasets. In this paper, adopting the mixed training strategy based on different datasets for the first time, we propose an encoder-decoder based general OD and OC segmentation network (named as GDCSeg-Net) with the newly designed multi-scale weight-shared attention (MSA) module and densely connected depthwise separable convolution (DSC) module, to effectively overcome these two problems. Experimental results show that our proposed GDCSeg-Net is competitive with other state-of-the-art methods on five different public fundus image datasets, including REFUGE, MESSIDOR, RIM-ONE-R3, Drishti-GS and IDRiD.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547985 | PMC |
http://dx.doi.org/10.1364/BOE.434841 | DOI Listing |
Graefes Arch Clin Exp Ophthalmol
January 2025
Department of Ophthalmology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, 160 Pujian Road, Shanghai, 200001, China.
Purpose: To evaluate the posterior scleral stiffness of different regions in high myopic eyes and to explore its associations with macular choroidal and peripapillary retinal nerve fiber layer (pRNFL) thickness and vasculature.
Methods: Thirty subjects with high myopic eyes and 30 subjects with low myopic eyes were included in this study. The elastic modulus of the macular and peripapillary sclera at the temporal, nasal, superior and inferior regions were determined via shear wave elastography (SWE).
PLoS One
January 2025
Department of Ophthalmology, University of Washington, Seattle, WA, United States of America.
To investigate macula and optic nerve head (ONH) mitochondrial metabolic activity using flavoprotein fluorescence (FPF) in normal, glaucoma suspect (GS), and open-angle glaucoma (OAG) eyes we performed a cross-sectional, observational study of FPF in normal, GS, and OAG eyes. The macula and ONH of each eye was scanned and analyzed with a commercially available FPF measuring device (OcuMet Beacon, OcuSciences Inc., Ann Arbor, MI).
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
January 2025
NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom.
Purpose: To investigate the effect of average intraocular pressure (IOP) on the true rate of glaucoma progression (RoP) in the United Kingdom Glaucoma Treatment Study (UKGTS).
Methods: UKGTS participants were randomized to placebo or Latanoprost drops and monitored for up to two years with visual field tests (VF, 24-2 SITA standard), IOP measurements, and optic nerve imaging. We included eyes with at least three structural or functional assessments (VF with <15% false-positive errors).
J Neuroophthalmol
November 2024
Ophthalmology Department (AC-C, MF-R, SA-A, RA, BS-D), Seu Maternitat, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain; Faculty of Medicine and Health Sciences (AC-C, SA-A, BS-D), Universitat de Barcelona, Barcelona, Spain; Fundació Per La Recerca Biomèdica-IDIBAPS (MF-R, SA-A, BS-D), Barcelona, Spain; and Ophthalmology Department (MS-G), Consorci Mar Parc de Salut de Barcelona, Barcelona, Spain.
Background: Autosomal Dominant Optic Atrophy (ADOA) is a hereditary optic neuropathy characterized by retinal ganglion cell degeneration and optic nerve fiber loss. This study examined the correlation between clinical and structural parameters in patients with ADOA using optical coherence tomography (OCT) and explored potential clinical biomarkers.
Methods: A cross-sectional, case-control observational study included 27 patients with ADOA and 27 age- and sex-matched healthy controls.
MethodsX
June 2025
Assistant Professor, Department of Electronics and Communication Engineering, Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology, Tamil Nadu, 600062, India.
Glaucoma, a severe eye disease leading to irreversible vision loss if untreated, remains a significant challenge in healthcare due to the complexity of its detection. Traditional methods rely on clinical examinations of fundus images, assessing features like optic cup and disc sizes, rim thickness, and other ocular deformities. Recent advancements in artificial intelligence have introduced new opportunities for enhancing glaucoma detection.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!