Trained lay volunteers may have value in supporting lifestyle change programs in the prevention of type 2 diabetes, but the potential health benefits (or harms) experienced by these lay volunteers have not been well described. This is important, as this is an appealing model in terms of workforce planning. The aim of the prespecified quantitative study reported here, was to examine the possible health benefits or harms experienced by these trained lay volunteers with type 2 diabetes. In a large type 2 diabetes prevention program, we recruited and trained 104 lay volunteers with type 2 diabetes themselves, to act as diabetes prevention mentors and codeliver the lifestyle intervention. Mentors made motivational telephone calls to 461 participants randomized to one of the trial arms to encourage lifestyle changes. Weight, diet, physical activity, well-being, quality of life, diabetes-specific self-efficacy, and glycaemic control were measured at baseline, 12 and 24 months. Average mentor age was 62.0 years, 57 (54.8%) were male, 92 (88.5%) were overweight or obese (BMI>30 kg/m). At 12 months, mentor dietary behaviors (fat and fiber intake) improved significantly, sedentary time spent fell significantly, and diabetes specific self-efficacy scores significantly increased. These significant improvements, with no evidence of harms, suggest lay volunteers with type 2 diabetes codelivering a lifestyle intervention, may themselves experience health benefits from volunteering.
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http://dx.doi.org/10.1177/10901981211048823 | DOI Listing |
Nutr Hosp
March 2025
Facultad de Medicina. Universidad de Castilla-La Mancha.
Introduction: currently there are changes in lifestyle that have been modifying the nutritional culture, moving away from the Mediterranean diet (DMed) and acquiring a more sedentary lifestyle, a fact that has contributed to a significant increase in risk factors. (CVRF) such as obesity and type 2 diabetes mellitus (DM2), and consequently to a global increase in metabolic syndrome (MS) and cardiovascular diseases (CVD), which in the 21st century reinforces being the first cause of morbidity and mortality To reduce this pandemic, a multidisciplinary approach is required focused on the application of primary and secondary prevention strategies for modifiable CVRFs, focused on nutritional promotion and education through the promotion of a healthier lifestyle and diet from childhood, as the one that encompasses the MedD. This dietary pattern, together with physical exercise, has been shown to contribute to the primary and secondary prevention of DM2 and coexisting CVRF.
View Article and Find Full Text PDFAIDS Care
March 2025
Division of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Older people with HIV (OPWH) have an increased risk of type 2 diabetes mellitus (T2DM). Understanding this is important to screen and initiate treatments. This study explored awareness of T2DM, perceived risk, and willingness to receive T2DM preventive education.
View Article and Find Full Text PDFEur J Prev Cardiol
March 2025
Division of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-gu, Seoul 05505, Republic of Korea.
Aims: Lipoprotein(a) [Lp(a)] is an emerging risk factor for major adverse cardiovascular events (MACE). However, evidence on MACE risk according to Lp(a) level in atherosclerotic patients is insufficient, and more data is needed about whether type 2 diabetes (T2DM) additionally contributes to this risk. We aimed to investigate the association between Lp(a) and MACE in atherosclerotic patients and compare the magnitude of Lp(a)-MACE association in the patients with and without T2DM.
View Article and Find Full Text PDFFront Immunol
March 2025
Institut D'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
T-regulatory-type-1 (TR1) cells are a subset of interleukin-10-producing but Foxp3 Treg cells that arise in response to chronic antigenic stimulation. We have shown that systemic delivery of autoimmune disease-relevant peptide-major histocompatibility complex class II (pMHCII)-coated nanoparticles (pMHCII-NP) triggers the formation of large pools of disease-suppressing Foxp3 TR1 cells from cognate T-follicular helper (TFH) cell precursors. Here we show that, upon treatment withdrawal, these Foxp3 TR1 cells spontaneously differentiate into a novel immunoregulatory Foxp3 TR1 subset that inherits epigenetic and transcriptional hallmarks of their precursors, including clonotypic T-cell receptors, and is distinct from other Foxp3 Treg subsets.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
January 2025
Department of ENT, Head and Neck Surgery, J. N. Medical College, KLE Academy of Higher Education and Research, Belagavi, Karnataka India.
Sensorineural hearing loss and type 2 diabetes are two frequent health issues that arise with ageing. Although both type 2 diabetes and gestational diabetes have been linked to hearing loss, a direct causal relationship has proven challenging to demonstrate. The intricate connection between gestational diabetes and sensorineural hearing loss will be outlined in the following article.
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