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Cell-free DNA Levels in Herpes Zoster: A Cross-sectional Longitudi-nal Study.
Acta Derm Venereol
January 2025
Ben Gurion University of the Negev, Faculty of Health Sciences, Beer-Sheva, Israel; Pediatric Dermatology Service, Soroka University Medical Center, Beer-Sheva, Israel.
This study investigates serum cell-free DNA fluctuations in patients with herpes zoster or post-herpetic neuralgia, offering insight into the tissue damage and inflammatory dynamics associated with these conditions. A single-centre combined cross-sectional and longitudinal study was conducted with 59 patients to assess cell-free DNA levels in herpes zoster and post-herpetic neuralgia. Cell-free DNA was extracted from blood samples of patients with herpes zoster or post-herpetic neuralgia and compared with healthy controls.
View Article and Find Full Text PDFPsychological stress dysfunction in women with premenstrual syndrome.
Heliyon
November 2024
Mental Health Education Center, Xidian University, Xi'an, China.
Premenstrual syndrome (PMS) encompasses a range of emotional, physiological, and behavioral symptoms that occur during the luteal phase of the menstrual cycle (MC) and resolve with the onset of menstruation. These symptoms, which can include fatigue, physical pain, anxiety, irritability, and depression, significantly affect women's daily lives and overall well-being. In severe cases, PMS can progress to premenstrual dysphoric disorder (PMDD), profoundly impairing quality of life.
View Article and Find Full Text PDFAcute Intermittent Porphyria in an Adolescent Patient: Diagnostic and Treatment Challenges.
Cureus
November 2024
Internal Medicine-Pediatrics, University of California Los Angeles, Los Angeles, USA.
Acute intermittent porphyria (AIP) is a rare inherited metabolic disorder caused by decreased activity of the enzyme porphobilinogen deaminase in the heme synthesis pathway. This leads to the accumulation of toxic porphyrin precursors, such as porphobilinogen and δ-aminolevulinic acid. Clinical manifestations typically include episodic bouts of severe neurovisceral pain and autonomic dysfunction.
View Article and Find Full Text PDFThe time-course changes in postural control variability between neck pain and asymptomatic dental students.
Sci Rep
December 2024
Neuromuscular Research Lab, Interdisciplinary Centre for the study of Human Performance (CIPER), Faculty of Human Kinetics, University of Lisbon, 1499-002, Oeiras, Portugal.
Changes in postural control associated with clinical practice or specific conditions such as the presence of neck pain remain unexplored in dental students. Therefore, this study aimed to explore the time-course changes in postural control complexity among dental students enrolled in clinical practice, comparing those with and without neck pain. We used an online Nordic Musculoskeletal Questionnaire for group allocation and center of pressure (CoP) oscillations with a tri-axial Bertec force plate.
View Article and Find Full Text PDFAperiodic spectral slope tracks the effects of brain state on saliency responses in the human auditory cortex.
Sci Rep
December 2024
Department of Neurosurgery, Baylor College of Medicine, Houston, USA.
Alteration of responses to salient stimuli occurs in a wide range of brain disorders and may be rooted in pathophysiological brain state dynamics. Specifically, tonic and phasic modes of activity in the reticular activating system (RAS) influence, and are influenced by, salient stimuli, respectively. The RAS influences the spectral characteristics of activity in the neocortex, shifting the balance between low- and high-frequency fluctuations.
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