Medicinal plants have been an integral and essential part of human life since ancient times. These have shaped the cultures around the globe. From underlings to elderly persons, everyone has come across to use herbal medicine for minor infection to deadly diseases. A wholesome approach is needed to maximize the knowledge about traditional resources. Thus, combining it with the new advents of technology is miraculous. Urinary tract infections (UTIs) are among the prevalent infections in the world. Increasing multi-drug resistance among uropathogens is quite problematic. The burning field of nanotechnology offers an enormous help in revolutionizing the diagnosis and treatment of the disease. The nanoparticles and nanocarriers can increase the bioavailability and efficacy of phytoconstituents targeted against the uropathogens. The present review focuses on herbal medicine and nanomaterials like nanoparticles, nanocarriers, nanoantibiotics as potent anti-bacterial agents against urinary tract infections.
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http://dx.doi.org/10.1166/jnn.2021.19002 | DOI Listing |
Methods Mol Biol
December 2024
Department of Microbiology and Plant Pathology, University of California, Riverside, CA, USA.
Transcriptional regulation allows cells to execute developmental programs, maintain homeostasis, and respond to intra- and extracellular signals. Central to these processes are promoters, which in eukaryotes are sequences upstream of genes that bind transcription factors (TFs) and which recruit RNA polymerase to initiate mRNA synthesis. Valuable tools for studying promoters include reporter genes, which can be used to indicate when and where genes are activated.
View Article and Find Full Text PDFJ Mol Histol
December 2024
Complementary and Integrative Medicine, Department of Traditional, Ankara Yıldırım Beyazıt University, Ankara, Türkiye, Turkey.
It is crucial to investigate new anti-diabetic agents and therapeutic approaches targeting molecules in potential signaling pathways for the treatment of Type 2 diabetes mellitus (T2DM). The objective of the study was to investigate the total phenolic content, antioxidant capacity, α-glucosidase, and α-amylase inhibitory activities of Bolanthus turcicus (B. turcicus), as well as their cytotoxic, anti-adipogenic, anti-diabetic, apoptotic, and anti-migration potential on adipocytes.
View Article and Find Full Text PDFMetabolomics
December 2024
School of Biosciences and the Birmingham Institute of Forest Research, University of Birmingham, Birmingham, B15 2TT, UK.
Introduction: Tree bacterial diseases are a threat in forestry due to their increasing incidence and severity. Understanding tree defence mechanisms requires evaluating metabolic changes arising during infection. Metabolite extraction affects the chemical diversity of the samples and, therefore, the biological relevance of the data.
View Article and Find Full Text PDFArch Toxicol
December 2024
Department of Medical Biotechnology, Gujarat Biotechnology University, GIFT City, Gandhinagar, 382355, Gujarat, India.
Chemotherapy, a cornerstone of cancer treatment, is frequently marred by its hepatotoxic effects, which can significantly impede therapeutic efficacy. This systematic review meticulously evaluates the hepatoprotective properties of phytochemicals and plant extracts against chemotherapy-induced liver damage, primarily in experimental animal models. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, an exhaustive search was conducted across databases like SCOPUS, PubMed, and Web of Science, culminating in the inclusion of 61 pertinent studies.
View Article and Find Full Text PDFVet Sci
December 2024
National Reference Laboratory of Veterinary Drug Residues (HZAU), Veterinary Medicine Research Center, Huazhong Agricultural University, Wuhan 430070, China.
The widespread utilization of antibiotic growth promoters (AGPs) boosts the growth rate of food animals and enhances human living standards. Nevertheless, it is accompanied by escalating antibiotic resistance. Consequently, there is an urgent demand to develop novel alternatives to growth promoters.
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